Early Management of Patients With Acute Ischemic Stroke

Published: October 2019
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  • Key Points
  • Graded Recommendations
    • Prehospital Stroke Management and Systems of Care
    • Emergency Evaluation and Treatment
    • Head and Neck Imaging
    • General Supportive Care and Emergency Treatment
    • IV Alteplase
    • Mechanical Thrombectomy
    • In-Hospital Management of AIS: General Supportive Care
    • In-Hospital Management of AIS: Treatment of Acute Complications
  • In-Hospital Institution of Secondary Stroke Prevention
  • Antithrombotic Treatment
  • Treatment of Hyperlipidemia
  • Tables
    • National Institutes of Health Stroke Scale
    • Options to Treat Arterial Hypertension in Patients with AIS Who Are Candidates for Emergency Reperfusion Therapy
    • Management of Symptomatic Intracranial Bleeding Occurring Within 24 Hours After Administration of IV Alteplase for Treatment of AIS
    • Management of Orolingual Angioedema Associated with IV Alteplase Administration for AIS
    • Eligibility Recommendations for IV Alteplase in Patients With AIS
    • Treatment of AIS: IV Administration of Alteplase
    • Risk Status
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Our mission is to build healthier lives, free of cardiovascular diseases and stroke. That single purpose drives all we do. AHA's Professional Membership is a made up of a robust group of cardiovascular professionals who participate in discovery and dissemination of science.

Created in 1997, the American Stroke Association is dedicated to prevention, diagnosis and treatment to save lives from stroke -- America's No. 5 killer and a leading cause of serious disability.


This pocket guide attempts to define principles of practice that should produce high-quality patient care. It is applicable to specialists, primary care, and providers at all levels. This pocket guide should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. The ultimate judgment concerning the propriety of any course of conduct must be made by the clinician after consideration of each individual patient situation. Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool.


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