Evaluation, Risk Stratification, and Management of Arrhythmogenic Cardiomyopathy
Heart Rhythm SocietyPublished: June 4, 2019
- Key Points
- Graded Treatment Recommendations
- Who to study
- Limitations of genetic testing
- Family history
- Age-related penetrance of disease in at-risk relatives
- Cascade cardiac investigations
- Cascade genetic testing
- Risk stratification and ICD decisions
- Medical therapies for right ventricular failure
- Antithrombotic therapy in ACM
- Arrhythmia management
- Role of catheter ablation
- Exercise and other ACM
- Amyloidosis
- Left ventricular noncompaction treatment
- Tables
- Classification of likelihood of pathogenicity of a variant
- Different methods for screening genes
- Minimal set of genes to be prioritized in ACM
- Diagnostic criteria for left ventricular noncompaction
- Figures
- Algorithm to consider the presence of ACM
- Arrhythmogenic cardiomyopathy
- Common pathway and genetic mutations in a patient with ACM according to the predominant ventricular dysfunction
- Cytoskeletal protein complexes within the cardiomyocyte costamere and Z-disk
- Modified Task Force criteria for ARVC – diagnostic categories major and minor criteria
- Representative 12-lead ECG obtained from ARVC patients with IRBBB and CRBBB
- Cumulative prevalence of disease expression in family members at risk of ARVC
- Genetic testing algorithm
- Summary of cascade family screening algorithm
- Implantable cardioverter defibrillator algorithm
- Algorithm for ventricular dysfunction and antithrombotic medical therapy in individuals with arrhythmogenic cardiomyopathy
- Medical therapy algorithm for arrhythmias
- Catheter ablation algorithm for individuals with ACM
- Exercise algorithm for individuals with ARVC
- METS associated with common types of endurance exercise
- Disease mechanisms for ACM
- Amyloidosis arrhythmia treatment algorithm
- Diagnosis and risk stratification of LVNC (a) and family and genetic evaluation of LVNC (b)
- LVNC treatment algorithm
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