Lupus Nephritis

Published: May 2012
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  • Key Points 
  • Case Definition for Lupus Nephritis 
  • Renal Biopsy and Histology 
  • Adjunctive Treatments
  • Recommendations for Induction of Improvement in Patients With ISN Class III/IV Lupus Glomerulonephritis
  • Recommendations for Induction of Improvement in Patients With Class IV Or IV/V Plus Cellular Crescents
  • Recommendations for Induction of Improvement in Patients With Class V “Pure Membranous” LN
  • Recommendations for Changing Therapies in Patients Who Do Not Respond Adequately to Induction Therapy 
  • Treatment of Lupus Nephritis in Patients Who Are Pregnant
  • Tables 
    • International Society of Nephrology/Renal Pathology Society 2003 Classification 
    • Indications For Renal Biopsy In Patients With Systemic Lupus Erythematosus 
    • Recommended Monitoring of Lupus Nephritis
  • Algorithms 
    • Class III/IV Induction Therapy
    • Treatment of Class III, IV, and V in Patients Who Are Pregnant
    • Treatment of Class V with Proteinuria ≥3g/24h
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The American College of Rheumatology's mission is advancing rheumatology! The organization represents over 9,400 rheumatologists and rheumatology health professionals around the world. The ACR offers its members the support they need to ensure that they are able to continue their innovative work by providing programs of education, research, advocacy, and practice support.

Description

This Guideline attempts to define principles of practice that should produce high-quality patient care. It is applicable to specialists, primary care, and providers at all levels. This Guideline should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. The ultimate judgment concerning the propriety of any course of conduct must be made by the clinician after consideration of each individual patient situation. Neither IGC, the American College of Rheumatology, nor the authors endorse any product or service associated with the distributor of this clinical reference tool.

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