Primary Aldosteronism Guidelines Pocket Guide - Guideline Central

Primary Aldosteronism

Endocrine SocietyPublished: July 14, 2025

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  • Background
  • Diagnosis
  • Tables
    • Prevalence of Primary Aldosteronism in Different Subgroups
    • Evidence for the Recommendation of Primary Aldosteronism Screening
    • PA Screening: ARR Cut Points According to Aldosterone and Renin Assay and Unit Measurements
    • Medications That Interfere With PA Screening and Their Effects on Aldosterone and Renin
    • Managing Interfering Antihypertensive Medications During PA Screening and Interpretation of Aldosterone, Renin and ARR
    • Description of the Most Commonly Used Aldosterone-Suppression Tests
    • Key Indices and Cutoffs for Adrenal Vein Sampling Interpretation
    • Comparisons of MRA and ENaC Inhibitors
  • Figures and Algorithms
    • How to Screen for PA in Individuals With Hypertension
    • Management of Adults With Hypertension in whom PA is Likely Based on Aldosterone, Renin and ARR
    • Initiating and Following MRA Therapy


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