Prosthetic Joint Infection

Published: October 2012
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  • Key Points
  • Definition of PJI
  • Preoperative Evaluation
  • Intraoperative Diagnosis
  • Treatment
    • Two-stage Exchange
    • One-stage Exchange
    • Permanent Resection
    • Amputation
    • PJI following
      • debridement and retention of the prosthesis
      • resection arthroplasty
      • one-stage exchange
      • amputation
  • Four Management Algorithms
  • Organism-specific Treatment Tables
    • Antimicrobials – preferred and alternate
    • Doses
    • Generics and Brand Names
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The Infectious Diseases Society of America (IDSA) represents physicians, scientists and other health care professionals who specialize in infectious diseases. IDSA's purpose is to improve the health of individuals, communities, and society by promoting excellence in patient care, education, research, public health, and prevention relating to infectious diseases.


This pocket guide attempts to define principles of practice that should produce high-quality patient care. It is applicable to specialists, primary care, and providers at all levels. This pocket guide should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. The ultimate judgment concerning the propriety of any course of conduct must be made by the clinician after consideration of each individual patient situation. Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool.


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