Selection of Optimal Adjuvant Chemotherapy and Targeted Therapy for Early Breast Cancer Guidelines Pocket Guide - Guideline Central

Selection of Optimal Adjuvant Chemotherapy and Targeted Therapy for Early Breast Cancer

American Society of Clinical OncologyPublished: May 20, 2024

A PDF version of this Pocket Guide is also available!
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  • Key Points
  • New Recommendations from 2024
  • Treatment Recommendations
    • Use of an Anthracycline-Taxane Regimen
    • Optimal-Dose Anthracycline Regimen for Patients for Whom a Taxane Is Contraindicated
    • Adding Gemcitabine or Capecitabine to an Anthracycline-Taxane Regimen
    • Capecitabine in Patients Age ≥65 Years
    • Cyclophosphamide-Methotrexate-Fluorouracil As an Alternative To Doxorubicin-Cyclophosphamide
    • Acceptable Adjuvant Chemotherapy Regimens for Patients with Higher-Risk Early Breast Cancer
    • Adjuvant Regimen When an Anthracycline Is Not Preferred
    • Patient Selection and Adjuvant Trastuzumab Therapy
    • Trastuzumab Plus Chemotherapy in Patients with Higher-Risk Her2-Positive Disease
    • Trastuzumab Plus Chemotherapy in Patients with Her2-Positive T1a-B N0 Disease
    • Selection of Chemotherapy Regimens in Patients Receiving Trastuzumab
    • Use of Trastuzumab and an Anthracycline-Containing Regimen
    • Concurrent Administration of Adjuvant Trastuzumab and Non-Anthracycline Chemotherapy Regimens
    • Trastuzumab-Based Chemotherapy or Trastuzumab Regimens For Patients at Higher Risk of Cardiotoxicity
    • Addition of Trastuzumab to Chemotherapy Regimens Not Evaluated in a Phase III Trial
    • Duration of Trastuzumab Therapy and Cardiac Function
    • Adjuvant Capecitabine
    • Adjuvant Pertuzumab
    • Adjuvant Neratinib
    • Adjuvant Abemaciclib


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