ASH Heparin-Induced Thrombocytopenia Guideline Summary - Guideline Central

Design and created by Guideline Central in participation with the American Society of Hematology.

Document Overview

Document Title: Heparin-Induced Thrombocytopenia

Authoring Society: American Society of Hematology

Document Publication Date: Nov 27, 2018

Page Last Reviewed/Updated: May 5, 2026

Document Type: Guideline

Country of Publication: United States

Full Text Freely Available: No

Full Text Guideline: www.bloodadvances.org/content/2/22/3360?sso-checked=true

Source Citation: Blood Adv (2018) 2 (22): 3360–3392.

Supplemental Implementation Resources

Document Scope, Criteria, and Use Cases

Document Objectives: These evidence-based guidelines of the American Society of Hematology (ASH) are intended to support patients, clinicians, and other health care professionals in their decisions about diagnosis and management of HIT.

Scope: Diagnosis, Management

Diseases/Conditions (MeSH)

D054556 - Venous Thromboembolism

D020246 - Venous Thrombosis

D006493 - Heparin

D006495 - Heparin, Low-Molecular-Weight

D054556 - Venous Thromboembolism

D020246 - Venous Thrombosis

D006493 - Heparin

D006495 - Heparin, Low-Molecular-Weight

Keywords: Venous Thromboembolism, anticoagulation, heparin, hit

Target Patient Population: asymptomatic patients for HIT, diagnosis and initial management of patients with suspected HIT, treatment of acute HIT, and special situations in patients with acute HIT or a history of HIT

Inclusion Criteria: Male, Female, Adolescent, Adult, Older Adult

Health Care Settings: Ambulatory, Hospital, Long Term Care, Outpatient

Intended Users: Nurse, Nurse Practitioner, Physician, Physician Assistant

Recommendation Development Processes & Methodology

Number of Source Documents: 135

Includes peer/external review process?: Yes

Includes public comment process?: No

Methodologist involvement?: Yes

Patient involvement?: No

Includes multi-disciplinary group?: Yes

Includes systematic review?: Yes

Grades quality of strength of evidence?: Yes

Grades quality of strength of recommendation?: Yes

Discloses funding source?: Yes

Discloses conflicts of interest?: Yes

Includes benefits/harms analysis with recommendations?: Yes