ADAPT Protocol for Cardiac Event Risk

Assesses chest pain patients for 2-hours for risk of cardiac event.

Troponin Negative at 0h and 2 h

EKG has no new Ischemic Changes

TIMI Score

Note: Since the TIMI Score includes cardiac enzyme and ST deviation, these are not listed below since they are already included above.

Age ≥ 65

≥ 3 CAD Risk Factors

  • Family history of coronary artery disease, hypertension, hypercholesterolemia, diabetes, or current smoker

Known CAD (Stenosis ≥ 50%)

Aspirin Use in Past 7 days

Severe angina (≥ 2 episodes in 24 hrs or persisting discomfort)


Source: Than M, et. al. 2-Hour Accelerated Diagnostic Protocol to Assess Patients With Chest Pain Symptoms Using Contemporary Troponins as the Only Biomarker : The ADAPT Trial. J Am Coll Cardiol. 2012 Jun 5;59(23):2091-8. doi: 10.1016/j.jacc.2012.02.035. Epub 2012 May 9.