SEDAN Score for Post-tPA Hemorrhage

Predicts risk of sICH after tPA

Blood Sugar

Early Infarct Signs on Initial CT

  • Hypoattenuation comprising <1/3 of the middle cerebral artery territory
  • Obscuration of the lentiform nucleus or Sylvian fissure
  • Loss of basal ganglion outline or insular ribbon
  • Cortical sulcal effacement

HyperDense Cerebral Artery Sign on Initial CT

Age > 75 Years

NIHSS ≥ 10


Source: Strbian D, Engelter S, Michel P, Meretoja A, Sekoranja L, Ahlhelm FJ, Mustanoja S, Kuzmanovic I, Sairanen T, Forss N, Cordier M, Lyrer P, Kaste M, Tatlisumak T.Symptomatic intracranial hemorrhage after stroke thrombolysis: the SEDAN score. Ann Neurol. 2012 May;71(5):634-41. doi: 10.1002/ana.23546.