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Number of attacks with objective clinical findings
One year of disease progression (retrospective or prospective)
Number of lesions with objective clinical evidence
Reasonable historical evidence of a prior attack
Are MRI result available
Periventricular T2 lesions
Juxtacordial T2 lesions
Infratentorial T2 lesions
Spinal Cord T2 lesion(s)
A new T2 and/or gadolinium-enhancing lesion on follow-up MRI, with reference to a baseline scan, irrespective of the timing of baseline scan.
Simultaneous presence of asymptomatic gadolinium-enhancing and nonenhancing lesions at any time.