A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

Recruitment Status
RECRUITING
(See Contacts and Locations)Verified March 2026 by AstraZeneca
Sponsor
AstraZeneca
Information Provided by (Responsible Party)
AstraZeneca
Clinicaltrials.gov Identifier
NCT06742723
Other Study ID Numbers:
D6972C00002
First Submitted
December 15, 2024
First Posted
December 18, 2024
Last Update Posted
April 29, 2026
Last Verified
March 2026

ClinicalTrials.gov processed this data on April 2026. Link to the current ClinicalTrials.gov record .

History of Changes

Study Details

Study Description

The purpose of this study is to investigate the efficacy, safety, and tolerability of baxdrostat in combination with dapagliflozin, compared with placebo and dapagliflozin, in reducing the risk of the composite endpoint of ≥ 50% sustained decline in eGFR, kidney failure, HF events, or CV death in participants with CKD and HTN.

This study consists of a 4-week dapagliflozin Run-in Period for participants untreated with SGLT2i at screening, and a double-blinded period where participants will receive either baxdrostat/dapagliflozin or placebo/dapagliflozin.

Site visits will take place at 2-, 4-, 8-, 16-, 34, and 52-weeks following randomisation. Thereafter visits will occur approximately every 4 months.

The study closure procedures will be initiated when the predetermined number of primary endpoint events is predicted to have occurred (N = 845) ie, the PACD. All randomised participants including any participants who have prematurely discontinued study intervention will be scheduled for a SCV within 6 weeks of the PACD. This period can be extended by AstraZeneca.

In case of premature discontinuation of blinded study intervention, participants will continue in the study and receive dapagliflozin 10 mg, unless the participant meets dapagliflozin specific discontinuation criteria. Baxdrostat/placebo should not be administered without dapagliflozin: baxdrostat/placebo should be interrupted if dapagliflozin is interrupted (baxdrostat/placebo may be resumed with dapagliflozin, if dapagliflozin is resumed), and should be permanently discontinued if dapagliflozin is permanently discontinued. If study intervention is temporarily or permanently discontinued, the participant should remain in the study, and it is important that the scheduled study visits (including the PTDV for participants with permanent discontinuation of study intervention) and data collection continue according to the study protocol until the SCV.

Condition or DiseaseIntervention/Treatment
Chronic Kidney Disease and Hypertension
Drug: Baxdrostat/dapagliflozinDrug: Placebo/dapagliflozin

Study Design

Study TypeInterventional
Actual Enrollment5000 participants
Design AllocationRandomized
Interventional ModelParallel Assignment
MaskingQuadruple
Primary PurposeTreatment
Official TitleA Phase III, Randomised, Double-blind, Placebo-controlled, Event-driven Study to Assess the Efficacy, Safety and Tolerability of Baxdrostat in Combination With Dapagliflozin Compared With Dapagliflozin Alone on Renal Outcomes and Cardiovascular Mortality in Participants With Chronic Kidney Disease and High Blood Pressure
Study Start DateMarch 2, 2025
Actual Primary Completion Date3yrs 6mos from now
Actual Study Completion Date3yrs 6mos from now

Groups and Cohorts

Group/CohortIntervention/Treatment
Baxdrostat/dapagliflozin
Participants randomised to the baxdrostat/dapagliflozin arm will initially receive a lower dose of baxdrostat and standard dose dapagliflozin. For participants that meet the up-titration criteria, baxdrostat may be up-titrated to higher dose.
Drug: Baxdrostat/dapagliflozin
baxdrostat tablet dapagliflozin tablet
Placebo/dapagliflozin
Patients will receive one dose of dapagliflozin comparator in combination with matching placebo daily.
Drug: Placebo/dapagliflozin
dapagliflozin tablet placebo tablet

Outcome Measures

Primary Outcome Measures
  1. To determine if baxdrostat/dapagliflozin is superior to placebo/dapagliflozin in reducing the risk of the composite endpoint of ≥ 50% sustained decline in eGFR, kidney failure, Heart Failure events(HF), or CV death.
    Time to the first occurrence of any of the components of the composite of: Kidney disease progression * ≥ 50% sustained decline in eGFR * Onset of kidney failure: * Sustained eGFR \< 15 mL/min/1.73 m2 or * Chronic dialysis treatment or * Receiving a kidney transplant or * Death with a renal primary cause (death due to kidney failure when dialysis is not given) CV events * HF with or without hospitalisation * CV death
Secondary Outcome Measures
  1. To determine if baxdrostat/dapagliflozin is superior to placebo/dapagliflozin in reducing the risk of the composite endpoint of ≥ 50% sustained decline in eGFR, kidney failure or CV death.
    To determine if baxdrostat/dapagliflozin is superior to placebo/dapagliflozin in reducing the risk of the composite endpoint of ≥ 50% sustained decline in eGFR, kidney failure, or CV death.
  2. To determine whether baxdrostat/dapagliflozin is superior to placebo/dapagliflozin in reducing the risk of the composite endpoint of kidney failure
    Time to the first occurrence of any of the components of the composite of: • Onset of kidney failure: * Sustained eGFR \< 15 mL/min/1.73 m2 or * Chronic dialysis treatment or * Receiving a kidney transplant or * Death with a renal primary cause (death due to kidney failure when dialysis is not given)
  3. To determine whether baxdrostat/dapagliflozin is superior to placebo/dapagliflozin in reducing the risk of MACE (Major Adverse Cardiac Events).
    Time to the first occurrence of any of the components of the composite of: CV (cardiovascular) death, HF (heart failure) with and without hospitalization, Myocardial Infraction, Stroke
  4. To determine whether baxdrostat/dapagliflozin is superior to placebo/dapagliflozin in reducing the risk of the composite endpoint of CV (cardiovascular) death.
    Time to the first occurrence of any of the components of the composite of CV (cardiovascular) death
  5. To determine whether baxdrostat/dapagliflozin is superior to placebo/dapagliflozin in reducing the risk of the composite endpoint of all-cause death.
    Time to the first occurrence of any of the components of the composite of all-cause death

Eligibility Criteria

Ages Eligible for Study(Adult, Older Adult)
Sexes Eligible for StudyAll
Accepts Healthy VolunteersNo
Inclusion Criteria
1. Participants of any sex and gender must be ≥ 18 years of age at the time of signing the informed consent. 2. Participants with (a) or (b): a) eGFR 30-59 mL/min/1.73 m² (local or central laboratory value) AND:
UACR ≥ 30 mg/g (3.39 mg/mmol) and \< 500 mg/g (56.5 mg/mmol) (central laboratory value only), or
UACR ≥ 500 mg/g (56.5 mg/mmol) and ≤ 5000 mg/g (565 mg/mmol) (local or central laboratory value), or
UPCR ≥ 700 mg/g (79 mg/mmol) and ≤ 7000 mg/g (790 mg/mmol) (local laboratory value only). (b) eGFR 60-75 mL/min/1.73 m² (local or central laboratory value) AND:
UACR ≥ 500 mg/g (56.5 mg/mmol) ) and ≤ 5000 mg/g (565 mg/mmol) (local or central laboratory value), or
UPCR ≥ 700 mg/g (79 mg/mmol) and ≤ 7000 mg/g (790 mg/mmol) (local laboratory value only) 3. \[obsolete\] 4. Participants with history of HTN and a SBP ≥ 130 mmHg (the most recent value within 4 weeks prior to screening or at the Screening Visit) and ≥ 120 mmHg at the Randomisation Visit. 5. Stable and maximum tolerated dose of an ACEi or an ARB (not both) for at least 4 weeks prior to Screening Visit. 6. Participants with: 1. Serum or plasma potassium ≥ 3.0 and ≤ 4.8 mmol/L if eGFR ≥ 45 mL/min/1.73 m2 (local or central laboratory values) 2. Serum or plasma potassium ≥ 3.0 and ≤ 4.5 mmol/L if eGFR \< 45 mL/min/1.73 m2 (local or central laboratory values)
Exclusion Criteria
1. Systolic blood pressure \> 180 mmHg, or diastolic BP \> 110 mmHg at screening. 2. Known hyperkalaemia, defined as potassium of ≥ 5.5 mmol/L within 3 months at screening. 3. Serum sodium \< 135 mmol/L (central or local laboratory values obtained within 4 weeks prior to screening or at the Screening Visit). 4\. Participants with T1DM will be excluded, except: 1. For US only: patients with T1DM treated with SGLT2i for at least 4 months, without DKA during that period, and who have experience with ketone monitoring are eligible for inclusion. 2. For Japan only: patients with T1DM treated with dapagliflozin 10 mg for at least 4 months, without DKA during the period of dapagliflozin treatment are eligible for inclusion. 5 Uncontrolled T2DM with HbA1c \> 10.5% (\> 91 mmol/mol) (central or local laboratory values obtained within 3 months prior to screening or at the Screening Visit). 6 New York Heart Association functional HF class IV at screening. 7 Stroke, transient ischaemic cerebral attack, valve implantation or valve replacement, carotid surgery, or carotid angioplasty, acute coronary syndrome, or hospitalisation for worsening heart failure within previous 3 months prior to randomisation. 8 Documented history of adrenal insufficiency. 9 Any dialysis (including for acute kidney injury) within 3 months prior to Screening Visit. 10 Any acute kidney injury within 3 months prior to the Screening Visit. 11 History of organ transplant or bone marrow transplant, or planned organ transplant within 6 months following randomisation (including kidney transplant). 12 Any clinical condition requiring systemic immunosuppression therapy other than maintenance therapy (stable for at least 3 months prior to Visit 1).

Contacts and Locations

Sponsors and CollaboratorsAstraZeneca
Locations
Research Site | Fairhope Alabama, United States, 36532Research Site | Surprise Arizona, United States, 85374Research Site | Tucson Arizona, United States, 85710Research Site | Beverly Hills California, United States, 90211Research Site | Canoga Park California, United States, 91303Research Site | Concord California, United States, 94520Research Site | Fremont California, United States, 94538Research Site | Fullerton California, United States, 92835Research Site | Inglewood California, United States, 90301Research Site | Los Alamitos California, United States, 90720Research Site | Los Angeles California, United States, 90073Research Site | San Diego California, United States, 92120Research Site | San Francisco California, United States, 94110Research Site | Stanford California, United States, 94305Research Site | Tarzana California, United States, 91356Research Site | Arvada Colorado, United States, 80002Research Site | Denver Colorado, United States, 80220Research Site | New Britain Connecticut, United States, 06051Research Site | Washington D.C. District of Columbia, United States, 20037Research Site | Boca Raton Florida, United States, 33487Research Site | Boynton Beach Florida, United States, 33435Research Site | Edgewater Florida, United States, 32132Research Site | Fort Lauderdale Florida, United States, 33316Research Site | Hollywood Florida, United States, 33021Research Site | Jacksonville Beach Florida, United States, 32250Research Site | Lake City Florida, United States, 32055Research Site | Lakeland Florida, United States, 33805Research Site | Melbourne Florida, United States, 32901Research Site | Miami Lakes Florida, United States, 33014Research Site | Ocoee Florida, United States, 34761Research Site | Port Charlotte Florida, United States, 33952Research Site | Port Orange Florida, United States, 32127Research Site | Riverview Florida, United States, 33578Research Site | Atlanta Georgia, United States, 30328Research Site | Atlanta Georgia, United States, 30344Research Site | Augusta Georgia, United States, 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8331143Research Site | Valdivia , Chile, 5090000Research Site | Victoria , Chile, 4720000Research Site | Viña del Mar , Chile, 2540488Research Site | Baotou , China, 014010Research Site | Beijing , China, 100034Research Site | Beijing , China, 100068Research Site | Beijing , China, CN-100083Research Site | Changchun , China, 130041Research Site | Changsha , China, 410008Research Site | Changsha , China, 410015Research Site | Changzhou , China, 272100Research Site | Chengdu , China, 610000Research Site | Chengdu , China, 610072Research Site | Chongqing , China, 400010Research Site | Dongwan , China, 523058Research Site | Fuyang , China, 236012Research Site | Guangzhou , China, 510280Research Site | Guangzhou , China, 510665Research Site | Guangzhou , China, 510800Research Site | Guangzhou , China, 511486Research Site | Haikou , China, 570311Research Site | Hefei , China, 230061Research Site | Hefei , China, 230601Research Site | Hengyang , China, 421001Research Site | Heze , China, 274099Research Site | Huaian , China, 223399Research Site | Jiaxing , China, 314001Research Site | Jilin , China, 132011Research Site | Jinan , China, 250021Research Site | Jining , China, 272006Research Site | Lanzhou , China, 730000Research Site | Linhai , China, 317000Research Site | Linyi , China, 276003Research Site | Luoyang , China, 471003Research Site | Nanchang , China, 330006Research Site | Nanning , China, Research Site | Ningbo , China, 315010Research Site | Ningbo , China, 315099Research Site | Ningbo , China, 315800Research Site | Panjin , China, 124009Research Site | Pingxiang , China, 337055Research Site | Shanghai , China, 200061Research Site | Shanghai , China, 200080Research Site | Shanghai , China, 201199Research Site | Shantou , China, 515041Research Site | Shenyang , China, 110004Research Site | Shenzhen , China, 518036Research Site | Shenzhen , China, 518053Research Site | Suzhou , China, 215004Research Site | Taian , China, 271099Research Site | Tianjin , China, CN-300052Research Site | Wanzhou , China, 404000Research Site | Wuhan , China, 430000Research Site | Wuhan , China, 430010Research Site | Wuxi , China, 214023Research Site | Xi'an , China, 710061Research Site | Xianyang , China, 750004Research Site | Yantai , China, 264000Research Site | Yinchuan , China, 750004Research Site | Zhengzhou , China, 450000Research Site | Zhongshan , China, 528401Research Site | Zhuzhou , China, 412007Research Site | Zigong , China, 643000Research Site | Barranquilla , Colombia, 080020Research Site | Barranquilla , Colombia, 80007Research Site | Bogotá , Colombia, 111411Research Site | Cali , Colombia, 760042Research Site | Medellín , Colombia, 050030Research Site | Medellín , Colombia, 050034Research Site | Montería , Colombia, 230002Research Site | Pasto , Colombia, 520002Research Site | Brandýs nad Labem , Czechia, 250 01Research Site | Brandýs nad Labem , Czechia, 250 01Research Site | Frýdek-Místek , Czechia, 738 01Research Site | Jilemnice , Czechia, 514 01Research Site | Krnov , Czechia, 794 01Research Site | Mladá Boleslav , Czechia, 293 01Research Site | Náchod , Czechia, 547 01Research Site | Olomouc , Czechia, 772 00Research Site | Pilsen , Czechia, 323 00Research Site | Prague , Czechia, 104 00Research Site | Prague , Czechia, 140 00Research Site | Prague , Czechia, 160 00Research Site | Slaný , Czechia, 274 01Research Site | Aalborg , Denmark, 9000Research Site | Aarhus , Denmark, 8200Research Site | Copenhagen E , Denmark, 2100Research Site | Herlev , Denmark, 2730Research Site | Herning , Denmark, 7400Research Site | Holbæk , Denmark, 4300Research Site | Kolding , Denmark, 6000Research Site | Cairo , Egypt, 11566Research Site | Cairo , Egypt, 11734Research Site | Cairo , Egypt, 4540046Research Site | Dakahlia , Egypt, 35516Research Site | Dakahlia , Egypt, 7650030Research Site | Amiens , France, 80054Research Site | Bordeaux , France, 33076Research Site | Boulogne-Billancourt , France, 92104Research Site | Brest , France, 29200Research Site | Clermont-Ferrand , France, 63003Research Site | Créteil , France, 94000Research Site | La Roche-sur-Yon , France, 85925Research Site | Le Mans , France, 72037Research Site | Limoges , France, 87042Research Site | Lyon , France, 69437Research Site | Marseille , France, 13005Research Site | Nantes , France, 44093Research Site | Nice , France, 06000Research Site | Nîmes , France, 30000Research Site | Paris , France, 75015Research Site | Paris , France, 75018Research Site | Pierre-Bénite , France, 69495Research Site | Poitiers , France, 86021Research Site | Quimper , France, 29000Research Site | Reims , France, 51100Research Site | Rouen , France, 76031Research Site | Saint-Priest-en-Jarez , France, 42270Research Site | Strasbourg , France, 67098Research Site | Tours , France, 37044Research Site | Vandœuvre-lès-Nancy , France, 54511Research Site | Bad Homburg , Germany, 61348Research Site | Bamberg , Germany, 96049Research Site | Berlin , Germany, 10117Research Site | Berlin , Germany, 10629Research Site | Berlin , Germany, 13509Research Site | Bochum , Germany, 44787Research Site | Brandenburg an der Havel , Germany, 14770Research Site | Brandenburg an der Havel , Germany, 14776Research Site | Dresden , Germany, 01279Research Site | Essen , Germany, 45122Research Site | Friedrichsthal , Germany, 66299Research Site | Görlitz , Germany, 02828Research Site | Göttingen , Germany, 37075Research Site | Hamburg , Germany, 21109Research Site | Hanover , Germany, 30449Research Site | Hanover , Germany, 30459Research Site | Hanover , Germany, 30625Research Site | Heidelberg , Germany, 69115Research Site | Heidelberg , Germany, 69120Research Site | Herne , Germany, 44625Research Site | Karlsburg , Germany, 17495Research Site | Karlsruhe , Germany, 76133Research Site | Karlsruhe , Germany, 76137Research Site | Landshut , Germany, 84034Research Site | Mainz , Germany, 55131Research Site | Obertshausen , Germany, 63179Research Site | Offenbach , Germany, 63065Research Site | Potsdam , Germany, 14473Research Site | Reinfeld (Holstein) , Germany, 23858Research Site | Rostock , Germany, 18057Research Site | Rotenburg (Wümme) , Germany, 27356Research Site | Stuttgart , Germany, 70376Research Site | Ulm , Germany, 89081Research Site | Wermsdorf , Germany, 04779Research Site | Zwenkau , Germany, 04442Research Site | Alexandroupoli , Greece, 68100Research Site | Athens , Greece, 11527Research Site | Heraklion , Greece, 71500Research Site | Ioannina , Greece, 45500Research Site | Pátrai , Greece, 26504Research Site | Thessaloniki , Greece, 54636Research Site | Thessaloniki , Greece, 54642Research Site | Thessaloniki , Greece, 57010Research Site | Budapest , Hungary, 1036Research Site | Budapest , Hungary, 1085Research Site | Budapest , Hungary, 1132Research Site | Budapest , Hungary, 1138Research Site | Dunaújváros , Hungary, 2400Research Site | Encs , Hungary, 3860Research Site | Győr , Hungary, 9024Research Site | Kaposvár , Hungary, 7400Research Site | Nyíregyháza , Hungary, 4400Research Site | Nyíregyháza , Hungary, 4405Research Site | Szeged , Hungary, 6724Research Site | Szeged , Hungary, 6725Research Site | Székesfehérvár , Hungary, 8000Research Site | Szolnok , Hungary, 5004Research Site | Zalaegerszeg , Hungary, 8900Research Site | Bangalore , India, 560060Research Site | Belagavi , India, 590010Research Site | Hyderabad , India, 500 034Research Site | Hyderabad , India, 500082Research Site | Kolkata , India, 700014Research Site | Kolkata , India, 700020Research Site | Madurai , India, 625107Research Site | Mumbai , India, 400026Research Site | New Delhi , India, 110001Research Site | New Delhi , India, 110017Research Site | New Delhi , India, 110029Research Site | New Delhi , India, 110029Research Site | Pune , India, 411013Research Site | Vijayawada , India, 520 008Research Site | Vijayawada , India, 522002Research Site | Afula , Israel, 18101Research Site | Ashdod , Israel, 7747629Research Site | Be’er Ya‘aqov , Israel, 70300Research Site | Haifa , Israel, 3109601Research Site | Haifa , Israel, 34362Research Site | Jerusalem , Israel, 91120Research Site | Kfar Saba , Israel, 44281Research Site | Nahariya , Israel, 22100Research Site | Petah Tikva , Israel, 49372Research Site | Rehovot , Israel, 76100Research Site | Tel Aviv , Israel, 6423906Research Site | Tiberias , Israel, 15208Research Site | Bassano del Grappa , Italy, 36031Research Site | Bologna , Italy, 40138Research Site | Desio , Italy, 20832Research Site | Foggia , Italy, 71100Research Site | Genoa , Italy, 16132Research Site | Modena , Italy, 41124Research Site | Naples , Italy, 80138Research Site | Novara , Italy, 28100Research Site | Padova , Italy, 35128Research Site | Pavia , Italy, 27100Research Site | Pisa , Italy, 56124Research Site | Pordenone , Italy, 33170Research Site | Roma , Italy, 00168Research Site | Rozzano , Italy, 20089Research Site | Torino , Italy, 10126Research Site | Tradate , Italy, 21049Research Site | Aira , Japan, 899-5421Research Site | Amagasaki-shi , Japan, 660-8550Research Site | Beppu-shi , Japan, 874-0011Research Site | Chigasaki-shi , Japan, 253-0044Research Site | Fujinomiya-shi , Japan, 418-0076Research Site | Hakodate-shi , Japan, 041-8680Research Site | Hamamatsu , Japan, 432-8580Research Site | Higashihiroshima-shi , Japan, 739-0041Research Site | Iizuka-shi , Japan, 820-8505Research Site | Inashiki-gun , Japan, 300-0395Research Site | Itabashi-ku , Japan, 173-0015Research Site | Iwata-shi , Japan, 438-8550Research Site | Kagoshima , Japan, 890-0073Research Site | Kamakura-shi , Japan, 247-0056Research Site | Kanazawa , Japan, 920-8530Research Site | Kashiwara-shi , Japan, 582-0005Research Site | Kasugai-shi , Japan, 486-8510Research Site | Kita-ku , Japan, 144-0001Research Site | Kitakyushu , Japan, 802-8555Research Site | Kitakyushu-shi , Japan, 807-0857Research Site | Kobe , Japan, 650-0017Research Site | Kobe , Japan, 650-0047Research Site | Kumagaya-shi , Japan, 360-0197Research Site | Kurashiki Shi , Japan, 701 0192Research Site | Kuse-gun , Japan, 613-0034Research Site | Kuwana-shi , Japan, 511-0061Research Site | Kyoto , Japan, 604-8845Research Site | Kyoto , Japan, 612-8555Research Site | Matsusaka-shi , Japan, 515-8557Research Site | Matsuyama , Japan, 790-0024Research Site | Matsuyama , Japan, 790-8524Research Site | Meguro-ku , Japan, 153-0051Research Site | Minatoku , Japan, 105-8471Research Site | Minatoku , Japan, 108-0073Research Site | Minokamo Shi , Japan, 505-8510Research Site | Miyakonojo-shi , Japan, 885-0035Research Site | Morioka , Japan, 020-0066Research Site | Nagaoka-shi , Japan, 940-8621Research Site | Naka , Japan, 311-0113Research Site | Narita-shi , Japan, 286-8520Research Site | Obihiro-shi , Japan, 080-0848Research Site | Osaka , Japan, 534-0021Research Site | Osaka , Japan, 543-0035Research Site | Osaka , Japan, 553-0003Research Site | Osaka , Japan, 558-8558Research Site | Osaka , Japan, 559-0012Research Site | Ōita , Japan, 870-0039Research Site | Ōme , Japan, 198-0042Research Site | Ōmihachiman , Japan, 523-0082Research Site | Saga , Japan, 849-8501Research Site | Sapporo , Japan, 003-0026Research Site | Sapporo , Japan, 060-0061Research Site | Sapporo , Japan, 062-0921Research Site | Sendai , Japan, 980-8574Research Site | Sendai , Japan, 981-3281Research Site | Shibuya-ku , Japan, 151-8528Research Site | Tanabe-shi , Japan, 646-8558Research Site | Toyoake-shi , Japan, 470-1192Research Site | Toyohashi , Japan, 441-8570Research Site | Tsu , Japan, 514-8507Research Site | Yaizu-shi , Japan, 425-8505Research Site | Yokohama , Japan, 236-0004Research Site | Yoshida-gun , Japan, 910-1193Research Site | Ampang , Malaysia, 68000Research Site | Cheras , Malaysia, 56000Research Site | Ipoh , Malaysia, 30990Research Site | Kajang , Malaysia, 43000Research Site | Kota Bharu , Malaysia, 15586Research Site | Kuala Lumpur , Malaysia, 59100Research Site | Seremban , Malaysia, 70300Research Site | Seri Manjung , Malaysia, 32040Research Site | Chihuahua City , Mexico, 31000Research Site | Cuauhtémoc , Mexico, 06700Research Site | Cuauhtémoc , Mexico, 06700Research Site | D.F , Mexico, 14000Research Site | Durango , Mexico, 34000Research Site | Guadalajara , Mexico, 44670Research Site | Guadalajara , Mexico, 44690Research Site | Mazatlán , Mexico, 82000Research Site | Mazatlán , Mexico, 82110Research Site | Mérida , Mexico, 97130Research Site | San Luis Potosí City , Mexico, 78250Research Site | Veracruz , Mexico, 91855Research Site | Zapopan , Mexico, 45138Research Site | Amersfoort , Netherlands, 3813 TZResearch Site | Amsterdam , Netherlands, 1105 AZResearch Site | Dordrecht , Netherlands, 3318 ATResearch Site | Groningen , Netherlands, 9713 GZResearch Site | Hilversum , Netherlands, 1212 VGResearch Site | Leiden , Netherlands, 2333 ZAResearch Site | Maastricht , Netherlands, 6229 HXResearch Site | Nieuwegein , Netherlands, 3435 CMResearch Site | Zwolle , Netherlands, 8025 ABResearch Site | Arequipa , Peru, AREQUIPA01Research Site | Bellavista , Peru, CALLAO 2Research Site | Chorrillos , Peru, Lima 9Research Site | Cusco , Peru, CUSCO 01Research Site | Lima , Peru, 14Research Site | Lima , Peru, 15036Research Site | Lima , Peru, 15046Research Site | Lima , Peru, 15046Research Site | Lima , Peru, 15074Research Site | Lima , Peru, 15088Research Site | Lima , Peru, LIMA 01Research Site | Piura , Peru, 20001Research Site | Cebu City , Philippines, 6000Research Site | Davao City , Philippines, 8000Research Site | Davao City , Philippines, PH-8000Research Site | Iloilo City , Philippines, 5000Research Site | Laguna , Philippines, 4024Research Site | Manadaluyong City , Philippines, 1552Research Site | Manila , Philippines, 1000Research Site | Quezon City , Philippines, 1101Research Site | Quezon City , Philippines, Research Site | San Fernando City , Philippines, 2000Research Site | Bialystok , Poland, 15-540Research Site | Gdynia , Poland, 81-157Research Site | Gdynia , Poland, 81-519Research Site | Gmina Świecie , Poland, 86-100Research Site | Jasło , Poland, 38-200Research Site | Katowice , Poland, 40-600Research Site | Katowice , Poland, 40-648Research Site | Katowice , Poland, 40-772Research Site | Krakow , Poland, 30-688Research Site | Krakow , Poland, 30-688Research Site | Krakow , Poland, 31-261Research Site | Krakow , Poland, 31-501Research Site | Krakow , Poland, 31-513Research Site | Lodz , Poland, 91-363Research Site | Lodz , Poland, 92-213Research Site | Lublin , Poland, 20-718Research Site | Piaseczno , Poland, 05-500Research Site | Poznan , Poland, 60-309Research Site | Poznan , Poland, 60-354Research Site | Poznan , Poland, 61-848Research Site | Pruszków , Poland, 05-800Research Site | Radom , Poland, 26-600Research Site | Rzeszów , Poland, 35-055Research Site | Szczecin , Poland, 70-111Research Site | Szczecin , Poland, 71-434Research Site | Szczecin , Poland, 71-526Research Site | Tczew , Poland, 83-110Research Site | Warsaw , Poland, 00-124Research Site | Warsaw , Poland, 00-719Research Site | Warsaw , Poland, 02-097Research Site | Warsaw , Poland, 02-507Research Site | Warsaw , Poland, 02-595Research Site | Warsaw , Poland, 02-798Research Site | Warsaw , Poland, 03-291Research Site | Wroclaw , Poland, 50-304Research Site | Wroclaw , Poland, 53-673Research Site | Żywiec , Poland, 34-300Research Site | Brasov , Romania, 500073Research Site | Bucharest , Romania, 042122Research Site | Bucharest , Romania, 060044Research Site | Bucharest , Romania, 22325Research Site | Bucharest , Romania, 22328Research Site | Cluj-Napoca , Romania, 400349Research Site | Craiova , Romania, 200349Research Site | Craiova , Romania, 200642Research Site | Oradea , Romania, 410469Research Site | Suceava , Romania, 720237Research Site | Timișoara , Romania, 300723Research Site | Al-Ahsa , Saudi Arabia, 36428Research Site | Dammam , Saudi Arabia, 31444Research Site | Riyadh , Saudi Arabia, 11211Research Site | Riyadh , Saudi Arabia, 11426Research Site | Riyadh , Saudi Arabia, 11462Research Site | Riyadh , Saudi Arabia, 12231Research Site | Riyadh/MENA , Saudi Arabia, 11426Research Site | Belgrade , Serbia, 11000Research Site | Belgrade , Serbia, 11000Research Site | Belgrade , Serbia, 11000Research Site | Belgrade , Serbia, 11070Research Site | Belgrade , Serbia, 11120Research Site | Kamenitz , Serbia, 21204Research Site | Kragujevac , Serbia, 34000Research Site | Kragujevac , Serbia, 34000Research Site | Niš , Serbia, 18000Research Site | Novi Sad , Serbia, 21000Research Site | Novi Sad , Serbia, 21000Research Site | Singapore , Singapore, 119074Research Site | Singapore , Singapore, 169608Research Site | Singapore , Singapore, 308433Research Site | Singapore , Singapore, 529889Research Site | Košice , Slovakia, 040 01Research Site | Kráľovský Chlmec , Slovakia, 077 01Research Site | Myjava , Slovakia, 90701Research Site | Nitra , Slovakia, 949 11Research Site | Prešov , Slovakia, 080 01Research Site | Prešov , Slovakia, 080 01Research Site | Púchov , Slovakia, 020 01Research Site | Trenčín , Slovakia, 91171Research Site | Trnava , Slovakia, 917 02Research Site | Žilina , Slovakia, 010 01Research Site | Bellville , South Africa, 7530Research Site | Benoni , South Africa, 1501Research Site | Bloemfontein , South Africa, 9301Research Site | Bloemfontein , South Africa, 9301Research Site | Cape Town , South Africa, 7570Research Site | Cape Town , South Africa, 7925Research Site | Durban , South Africa, 4091Research Site | Durban , South Africa, 4092Research Site | Durban , South Africa, 4450Research Site | Johannesburg , South Africa, 1827Research Site | KwaDukuza , South Africa, 4449Research Site | Lenasia , South Africa, 1827Research Site | Midrand , South Africa, 1685Research Site | Newton , South Africa, 2113Research Site | Parow , South Africa, 7505Research Site | Ansan-si , South Korea, 15355Research Site | Anyang-si , South Korea, 14068Research Site | Busan , South Korea, 49241Research Site | Cheonan-si , South Korea, 31151Research Site | Goyang-si , South Korea, 10380Research Site | Gwangju , South Korea, 61469Research Site | Seongnam-si , South Korea, 13620Research Site | Seoul , South Korea, 03722Research Site | Seoul , South Korea, 04401Research Site | Seoul , South Korea, 07061Research Site | Wŏnju , South Korea, 26426Research Site | Yangsan , South Korea, 50612Research Site | A Coruña , Spain, 15006Research Site | Almería , Spain, 4009Research Site | Badalona , Spain, 08916Research Site | L'Hospitalet de Llobregat , Spain, 08907Research Site | Majadahonda , Spain, 28222Research Site | Málaga , Spain, 29010Research Site | Palma deMallorca , Spain, 07010Research Site | Pamplona , Spain, 31008Research Site | Seville , Spain, 41013Research Site | Seville , Spain, 41071Research Site | Valencia , Spain, 46010Research Site | Valencia , Spain, 46017Research Site | Huddinge , Sweden, 141 57Research Site | Karlstad , Sweden, 651 85Research Site | Linköping , Sweden, 581 85Research Site | Stockholm , Sweden, 18288Research Site | Uppsala , Sweden, 751 85Research Site | Vaxjo , Sweden, 352 34Research Site | New Taipei City , Taiwan, 220Research Site | Taichung , Taiwan, 402Research Site | Taichung , Taiwan, 433004Research Site | Taipei , Taiwan, 10002Research Site | Taipei , Taiwan, 110Research Site | Taipei , Taiwan, TAIWANResearch Site | Taoyuan , Taiwan, 333Research Site | Yung Kang City , Taiwan, 71044Research Site | Bangkok , Thailand, 10330Research Site | Bangkok , Thailand, 10400Research Site | Bangkok , Thailand, 10700Research Site | Banphaeo , Thailand, 74120Research Site | Hat Yai , Thailand, 90110Research Site | Khon Kaen , Thailand, 40002Research Site | Mueang , Thailand, 50200Research Site | Phutthamonthon , Thailand, 73170Research Site | Ubonratchathani , Thailand, 34000Research Site | Adana , Turkey (Türkiye), 01060Research Site | Adapazarı , Turkey (Türkiye), 54100Research Site | Altındağ , Turkey (Türkiye), 06230Research Site | Ankara , Turkey (Türkiye), 06530Research Site | Antalya , Turkey (Türkiye), 07100Research Site | Haliliye , Turkey (Türkiye), 63040Research Site | Kahramanmaraş , Turkey (Türkiye), 46040Research Site | Kayseri , Turkey (Türkiye), 38039Research Site | Kocaeli , Turkey (Türkiye), 41380Research Site | Şahinbey , Turkey (Türkiye), 27310Research Site | Chernivtsі , Ukraine, 58002Research Site | Ivano-Frankivsk , Ukraine, 76008Research Site | Kyiv , Ukraine, 01601Research Site | Kyiv , Ukraine, 03037Research Site | Kyiv , Ukraine, 03049Research Site | Kyiv , Ukraine, 03057Research Site | Kyiv , Ukraine, 04050Research Site | Ternopil , Ukraine, 46000Research Site | Ternopil , Ukraine, 46001Research Site | Uzhhorod , Ukraine, 88014Research Site | Uzhhorod , Ukraine, 88018Research Site | Vinnytsia , Ukraine, 21001Research Site | Vinnytsia , Ukraine, 21009Research Site | Vinnytsia , Ukraine, 21029Research Site | Zhytomyr , Ukraine, 10002Research Site | Bradford , United Kingdom, BND9 6RJResearch Site | Bristol , United Kingdom, BS105NBResearch Site | Canterbury , United Kingdom, CT1 3NGResearch Site | Cardiff , United Kingdom, CF14 4XWResearch Site | Dundee , United Kingdom, DD1 9SYResearch Site | Glasgow , United Kingdom, G51 4TFResearch Site | Hounslow , United Kingdom, TW3 3LNResearch Site | London , United Kingdom, E1 1BBResearch Site | London , United Kingdom, SE5 9RSResearch Site | Salford , United Kingdom, M6 8HDResearch Site | Southampton , United Kingdom, SO16 6YDResearch Site | Swansea , United Kingdom, SN6 6NLResearch Site | Da Nang , Vietnam, 550000Research Site | Haiphong , Vietnam, 180000Research Site | Hanoi , Vietnam, 10000Research Site | Ho Chi Minh City , Vietnam, 700000Research Site | Ho Chi Minh City , Vietnam, 700000Research Site | Ho Chi Minh City , Vietnam, 700000Research Site | Ho Chi Minh City , Vietnam, 70000Research Site | Rach Gia , Vietnam, 920000