Acute Gout

Publication Date: September 28, 2012

Key Points

Key Points

  • Gout is one of the most common rheumatic diseases of adulthood, with a self-reported prevalence in the US recently estimated at 3.9% of adults (~8.3 million people).
  • Ideally, pharmacologic treatment of an acute gouty attack should be initiated within 24 hours of onset.
  • Either NSAIDs, colchicine or corticosteroids can be used for treatment of acute gouty arthritis.
  • When colchicine is used, it is best to use earlier in the attack (within 36 hours) rather than later, and it should be dosed 1.2 mg, followed by 0.6 mg 1 hour later. Then it can be continued until the attack resolves with continued dosing based on renal function.
  • Ongoing pharmacologic ULT should not be interrupted during an acute gout attack.

Descriptors of Acute Gout Attack

...scriptors of Acute Gout Attack...

...se Scenarios for Defining Acute Gouty Arthritis...


Treatment

...atment

...1. Management of an Acute Gout Attack...


...mendations for Combination Therapy Approach to Acu...

...mbination therapy is an appropriate option...

...le combination therapy approaches include...

...or patients not responding adequately to i...


...2. Acute Gouty Arthritis Attack Man...


...cologic Monotherapy Options for an Acute Attac...