Acute Gout
Publication Date: September 28, 2012
Key Points
Key Points
- Gout is one of the most common rheumatic diseases of adulthood, with a self-reported prevalence in the US recently estimated at 3.9% of adults (~8.3 million people).
- Ideally, pharmacologic treatment of an acute gouty attack should be initiated within 24 hours of onset.
- Either NSAIDs, colchicine or corticosteroids can be used for treatment of acute gouty arthritis.
- When colchicine is used, it is best to use earlier in the attack (within 36 hours) rather than later, and it should be dosed 1.2 mg, followed by 0.6 mg 1 hour later. Then it can be continued until the attack resolves with continued dosing based on renal function.
- Ongoing pharmacologic ULT should not be interrupted during an acute gout attack.
Descriptors of Acute Gout Attack
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...Case Scenarios for Defining Acute Gouty...
Treatment
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...1. Management of an Acute Gout Attack...
...ble 2. Recommendations for Combination Ther...
...al combination therapy is an appropr...
...bination therapy approaches include...
...s not responding adequately to initial phar...
...2. Acute Gouty Arthritis Attack Management...
...Pharmacologic Monotherapy Options for an Acute...