Acute Gout
Publication Date: September 28, 2012
Key Points
Key Points
- Gout is one of the most common rheumatic diseases of adulthood, with a self-reported prevalence in the US recently estimated at 3.9% of adults (~8.3 million people).
- Ideally, pharmacologic treatment of an acute gouty attack should be initiated within 24 hours of onset.
- Either NSAIDs, colchicine or corticosteroids can be used for treatment of acute gouty arthritis.
- When colchicine is used, it is best to use earlier in the attack (within 36 hours) rather than later, and it should be dosed 1.2 mg, followed by 0.6 mg 1 hour later. Then it can be continued until the attack resolves with continued dosing based on renal function.
- Ongoing pharmacologic ULT should not be interrupted during an acute gout attack.
Descriptors of Acute Gout Attack
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Treatment
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...mbination therapy is an appropriate option for...
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...not responding adequately to initial pharmacolo...
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