Today we’re showcasing some of the most popular geriatric-related articles posted recently across medical journals.

A Novel Sex-Specific Association Between Insulin Resistance and Depressive Symptoms in Older Adults: The Potential Mediating Role of Vascular Endothelial Growth Factor

  • Journal of Affective Disorders, April 2025
  • Description: Depression and insulin resistance are increasingly identified as interconnected aging conditions. Using the triglyceride-glucose (TyG) index as a marker for insulin resistance, the study revealed that depressive symptoms were linked to higher levels of vascular endothelial growth factor (VEGF) and monocyte chemoattractant protein-1, and lower levels of anti-inflammatory cytokines. The TyG index showed notable connections to depressive symptoms and VEGF in women, highlighting a potential metabolic-inflammatory pathway specific to older women.
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Daily Life Stressors in Long Term Care: A View From the Inside

  • The American Journal of Geriatric Psychiatry, April 2025
  • Description: Residents in long-term care facilities, along with their families and friends, frequently have concerns about care and comfort. Because psychiatric assessments in these settings tend to focus on clinical issues, broader concerns from residents often go unheard by mental health professionals. These inquiries are typically addressed to nursing staff, and so geriatric psychiatrists may remain unaware. The article’s author, now living independently within a continuing care community, provides insight into the routine realities of living in long-term care.
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Expanded Care Planning Paradigm for Older Adults with Type 2 Diabetes: Rationale, Design, and Protocol of the PREPARE for Your Diabetes Care Randomized Trial

  • Contemporary Clinical Trials, April 2025
  • Description: Older adults living with type 2 diabetes are increasingly likely to experience treatment-related hypoglycemia and related complications from falls. A care paradigm for older adults can help reduce treatment-related issues from type 2 diabetes.
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Discrepancies in Medication Lists After Hospital Discharge in Patients with Multiple Long-term Conditions

  • Research in Social & Administrative Pharmacy, March 2025
  • Description: Patients with multiple long-term conditions often experience poor informational transition from hospital to home. Medication safety is a primary concern among this population. The study found that nearly all patients were observed to experience medication discrepancies.
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Psychotropic Comedication Trends in Long-Term Lithium Treatment for Older Adults with Bipolar Disorder: A 10-Year Analysis

  • Journal of Affective Disorders, March 2025
  • Description: The article provides insights gleaned from an examination of 15 years of psychotropic comedication prescription data among 166 older adults with bipolar disorder treated with lithium. Benzodiazepines were found most frequently prescribed, which is concerning for long-term use.
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Extra-abdominal CT Imaging Indicates Increased Severity of Illness in Advanced Age Patients Requiring Emergency Abdominal Surgery

  • American Journal of Surgery, March 2025
  • Description: Abdominal sepsis often leads to neurological and respiratory complications in older adults. We propose that geriatric patients with abdominal sepsis who receive imaging beyond the abdominal area may experience a higher overall illness severity.
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The Impact of Loneliness on Late-Life Depression and Anxiety During the COVID-19 Pandemic

  • The American Journal of Geriatric Psychiatry, January 2025
  • Description: The featured study delves into the effects loneliness during COVID-19 may have caused for older adults, as it relates to depression, anxiety, and sleep health. The study found that older adults with moderate to low levels of loneliness during the pandemic experienced milder symptoms than those who faced higher levels of loneliness. The findings highlight the consideration for loneliness interventions and assessments in the event of future pandemic lock-down events.
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Look forward to more journal-focused topics in the coming weeks. 

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