Consistent engagement with current medical literature enables clinicians to apply the latest evidence-based treatment and integrate research into clinical practice. This approach enhances patient outcomes by facilitating more effective and individualized care.
Today, we’re showcasing some of the latest rheumatology-related articles published recently across medical journals. The topics in today’s rundown include rheumatoid arthritis, gout, and ankylosing spondylitis. Some article descriptions were edited for brevity and clarity.
Rheumatoid Arthritis Articles
Golimumab for the Treatment of Rheumatoid Arthritis: A Narrative Review of Pivotal Randomized Trials and Real-World Studies
- Rheumatology and Therapy, May 2026
- Description: This narrative review presents the efficacy and safety outcomes from the golimumab pivotal randomized controlled trials (RCTs) that evaluated the subcutaneous and intravenous formulations.
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Heat-Not-Burn Tobacco Induces Protein Post-Translational Modifications and Apoptosis in Cronchial Cells: Possible Role in Rheumatoid Arthritis
- RMD Open, May 2026
- Description: Smoking is recognised as one of the strongest environmental risk factors for the development of rheumatoid arthritis. [The researchers] aimed to evaluate whether heat-not-burn cigarettes are associated with an increase in post-translational modifications and their effects on cell death mechanisms, such as apoptosis.
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The Painful Truth: The Relationship between Non-Articular Pain and Patient Global Assessment before and after Initiating a New DMARD for Active Rheumatoid Arthritis
- Arthritis Care & Research, May 2026
- Description: Non-articular pain (NAP) may contribute to patient global assessment (PtGA), confound disease activity assessment, and influence treatment decisions. [The researchers’] aims were to 1) evaluate the association between NAP and PtGA in adults with active rheumatoid arthritis starting a new DMARD; and 2) determine the extent this relationship is mediated by pain intensity.
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Impact of Disease Duration on Forefoot Involvement in Rheumatoid Arthritis Remission: Clinical, Ultrasound, and Radiographic Insights
- BMC Rheumatology, May 2026
- Description: Rheumatoid arthritis (RA) frequently affects the forefoot, causing pain and deformity even in remission. Subclinical inflammation may persist and vary with disease duration. This study aimed to compare clinical, ultrasound, and radiographic features of the forefoot in RA remission with metatarsalgia according to disease duration (< 10 vs. ≥ 10 years).
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Gout Articles
Walking for Gout Prevention: What Are Potential Mechanisms and Practical Applications?
- Rheumatology, April 2026
- Description: While genetic susceptibility cannot be altered, lifestyle interventions remain a viable target for primary prevention or delaying gout onset. In this context, the study by Wu et al., featured in the current issue of Rheumatology, provides evidence suggesting that increased walking activity may attenuate the risk of incident gout, even among individuals with high genetic susceptibility.
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Duration and Dose of Allopurinol Needed to Attain the Serum Urate Target in Gout
- Scandinavian Journal of Rheumatology, April 2026
- Description: [Researchers] studied patients in the NOR-Gout prospective cohort with a recent gout flare and increased SU (> 360 μmol/L). Patients escalated allopurinol dosage until reaching the SU treatment target of <360 µmol/L, switching, if needed, to febuxostat.
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Recombinant Human Tumor Necrosis Factor Receptor Fusion Protein as Treatment for Gout Flare
- International Journal of Rheumatic Diseases, April 2026
- Description: [This was a] single-center, prospective, random, open-label study of acute gout patients treated with etanercept. The treatment protocol involved subcutaneous administration of etanercept at a dose of 25 mg twice in five days.
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Ankylosing Spondylitis Articles
Fat Infiltration is Moderately Associated with Disease Activity in Ankylosing Spondylitis: A Cross-sectional Study: Lumbar Paraspinal Muscles in Ankylosing Spondylitis
- Medicine, May 2026
- Description: To assess the association between lumbar paraspinal muscle (multifidus and erector spinae) and psoas muscle volume and fatty infiltration with clinical features in patients with ankylosing spondylitis. This study included 35 patients with ankylosing spondylitis and 25 healthy controls.
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Celiac Trunk Thrombosis and Splenic Infarction in a Patient with Ankylosing Spondylitis Under Adalimumab: A Case Report
- International Journal of Emergency Medicine, April 2026
- Description: A 45-year-old male with ankylosing spondylitis under adalimumab presented with acute epigastric pain and bilious vomiting. Contrast-enhanced computed tomography with angiography revealed a 1.5 cm thrombus at the celiac trunk trifurcation with subtotal occlusion of the splenic and common hepatic arteries, high-grade stenosis of the left gastric artery, and subsequent splenic infarction. The patient was managed conservatively with anticoagulation and supportive care, with gradual clinical improvement.
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Clinical Characteristics and Management of Spinal Fractures in Patients with Ankylosing Spondylitis: A Retrospective Cohort Study
- Journal of Orthopaedic Surgery and Research, April 2026
- Description: Patients with ankylosing spondylitis (AS) are prone to spinal fractures with unique characteristics. This retrospective cohort study aimed to characterize the demographic and clinical features of spinal fractures in AS patients; analyze fracture patterns, including anatomical distribution, morphology, and association with spinal cord injury (SCI); and evaluate surgical approaches and their associated complications.
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Look forward to more journal-focused topics in the coming weeks.
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