The International Society on Thrombosis and Hemostasis (ISTH) recently opened a guidance manuscript regarding managing perioperative bleeding to public comment. The guidance manuscript, Use of Factor Concentrates for the Management of Perioperative Bleeding: Guidance from the ISTH SCC Subcommittee on Perioperative and Critical Care Thrombosis and Hemostasis, is available to physicians, scientists, and other members of the health community to review.

Click here to view the ISTH guidance manuscript.

Click here to view the public comment submission form.

The public comment window is open through July 9, 2026.