Today we’re showcasing some of the most recent pulmonology-related articles posted recently across medical journals. We broke today’s rundown into three sections focused on a different pulmonary topic: Asthma, COPD, and obstructive sleep apnea. The articles were featured in publications including, International Immunopharmacology, Respiratory Medicine, and the Journal of Asthma and Allergy. 

The nine article range from a study on allergen immunotherapy in patients with severe allergic asthma, to identifying COPD patients at risk of atrial fibrillation, and more.

Asthma

Selection of Behavior Change Techniques for Asthma Medication Adherence Apps: Evidence-Based Design Study

  • JMIR mHealth and uHealth, September 2025
  • Description: Medication nonadherence is common among adults prescribed preventer inhalers for asthma and has a variety of influences, creating a need to identify what components behavior change technique apps should include to effectively tackle each influence.
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Short-term Therapeutic Effectiveness of Tezepelumab in Patients with Severe Asthma: A Real-world Study

  • International Immunopharmacology, September 2025
  • Description: Tezepelumab is a fully human monoclonal antibody which specifically binds to thymic stromal lymphopoietin (TSLP), thus effectively inhibiting its pleiotropic pathogenic actions. Tezepelumab has been licensed for add-on biologic therapy of severe asthma, regardless of biomarker levels or phenotype expression.
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Safety and Effectiveness of Allergen Immunotherapy in Patients with Severe Allergic Asthma

  • Journal of Asthma and Allergy, September 2025
  • Description: This study aimed to gather real-world evidence on the safety and effectiveness of allergen immunotherapy in individuals with severe asthma caused by sensitization to at least 1 allergen, who were either currently undergoing AIT or had received it within the past five years.
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COPD

Feasibility and Acute Physiological Responses to Supramaximal High-intensity Interval Training in COPD: A Randomised Crossover Trial

  • ERJ Open Research, September 2025
  • Description: This randomised crossover trial examined the feasibility and physiological responses of a novel supramaximal high-intensity interval-training (SupraHIIT) protocol compared with moderate-intensity continuous training (MICT) in people with COPD and matched healthy controls (HCs).
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Risk of Major Adverse Cardiovascular Events During Acute Streptococcus Pneumoniae Infection in COPD Patients

  • JACC Advances, September 2025
  • Description: Patients with chronic obstructive pulmonary disease (COPD) are at an increased risk of severe complications and death from community-acquired pneumonia such as Streptococcus pneumoniae. Previous studies suggest that acute infection heightens the short-term risk of cardiovascular events.
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ECG-based Identification of COPD Patients at Risk for Atrial Fibrillation and Its Impact on Adverse Clinical Outcomes – A Subgroup Analysis of the Prospective Multicenter COSYCONET Cohort

  • Respiratory Research, September 2025
  • Description: Atrial fibrillation (AF) frequently occurs in patients with chronic obstructive pulmonary disease and is associated with adverse clinical outcomes. We aimed to identify patients at risk for AF using amplified p-wave duration analysis on electrocardiogram as a non-invasive tool to diagnose an atrial cardiomyopathy which is an established risk factor for AF.
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Obstructive Sleep Apnea

Asthma-OSA Overlap Syndrome: A Distinct Endophenotype?

  • Respiratory Medicine, September 2025
  • Description: Asthma and obstructive sleep apnea (OSA) are two respiratory diseases that often may coexist, resulting in Alternative Overlap Syndrome (aOVS), which is still underestimated and underdiagnosed.
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Reduction of Carbonic Anhydrase Activity is Associated with Amelioration of Obstructive Sleep Apnea

  • Sleep & Breathing, September 2025
  • Description: The carbonic anhydrase (CA) enzyme plays an important role in the equilibration of carbon dioxide and bicarbonate (HCO) under the production of H ions. Emerging evidence suggest that CA activity may play a fundamental regulatory role on respiratory control mechanisms in obstructive sleep apnea (OSA). Clinical trials suggest that CA inhibitors significantly reduce OSA.
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Anesthesiologic Management of Adult and Pediatric Patients with Obstructive Sleep Apnea

  • Healthcare, September 2025
  • Description: This comprehensive review summarizes current evidence on the anesthesiologic management of OSA patients, focusing on preoperative screening, risk stratification, intraoperative considerations, and postoperative care.
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Look forward to more journal-focused topics in the coming weeks. 

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