Antibiotic Stewardship

Publication Date: April 13, 2016

Background

Background

Approaches to optimize the use of both existing antibiotics and newly developed antibiotics are of critical importance to ensure that we continue to reap their benefits and provide the best care to patients.

Antibiotic stewardship has been defined as “coordinated interventions designed to improve and measure the appropriate use of antibiotic agents by promoting the selection of the optimal antibiotic drug regimen including dosing, duration of therapy, and route of administration.”

The benefits of antibiotic stewardship include improved patient outcomes, reduced adverse events including Clostridium difficile infection (CDI), improvement in rates of antibiotic susceptibilities to targeted antibiotics, and optimization of resource utilization across the continuum of care.

IDSA and SHEA strongly believe that antibiotic stewardship programs are best led by infectious disease physicians with additional stewardship training.

Interventions

...nterventions...

...ecommend preauthorization and/or p...


...against relying solely on didactic...


...Comparison of Preauthorization and...


...est antibiotic stewardship programs (AS...


...gest ASPs implement interventions to...


...ntibiotic stewardship intervention...


...the use of strategies (e.g., antib...


...gest incorporation of computerized...


We suggest against the use of antibiotic c...


Optimization

...ptimizati...

...at hospitals implement pharmacokinetic monitori...


...d suggest the same for vancomycin. (W - Weak,...


In hospitalized patients, we suggest ASPs advocate...


...recommend ASPs implement programs to increase...


...h a history of β-lactam allergy, we sugges...


We recommend that ASPs implement guidelin...


Microbiology and Laboratory Diagnostics

Microbiology and Laboratory D...

...opment of stratified antibiograms o...


...uggest selective and cascade reporti...


...suggest the use of rapid viral testing...


...ggest rapid diagnostic testing in addition to conv...


...CUs with suspected infection, we sugges...


...atients with hematologic malignancy...


Measurement

Measureme...

...suggest monitoring antibiotic use as...


...nd measuring antibiotic costs based...


...that consider the goals and size of the syndrome...


...le 2. Possible Metrics for Evaluat...


Special Populations

...pecial Popula...

...e suggest ASPs develop facility-sp...


...implementation of ASP interventions to impr...


...rsing homes and skilled nursing facilities, we su...


...lementation of antibiotic stewardship interve...


...ally ill patients, we suggest ASPs provide sup...