Chemotherapy and Targeted Therapy for Patients With Human Epidermal Growth Factor Receptor 2–Negative Metastatic Breast Cancer That is Either Endocrine-Pretreated or Hormone Receptor–Negative

Patients with hormone receptor-positive HER2-negative metastatic breast cancer who are refractory to endocrine therapy and have received at least 2 prior lines of chemotherapy for metastatic disease may be offered sacituzumab govitecan. (Quality of Evidence - Medium) ( EB , , B , S )