Managing Adiposity-Related Diseases

Publication Date: February 28, 2024

Key Points

Key Points

  • Among the many conditions caused or worsened by excess adipose tissue (AT), the most prevalent are:
    • Cardiovascular disease (CVD)
    • Elevated blood sugar
    • High blood pressure
    • Dyslipidemia
    • Metabolic dysfunction-associated steatotic liver disease (MASLD)
    • Cancer
    • Obesity and stress: cause and effect
    • Psychiatric disease
  • These conditions are also largely improved, even prevented, by weight loss.
  • It is therefore recommended that weight loss be an integral part of management whenever excess AT accompanies any of these conditions.

Simplified Mechanism of Obesity, Insulin Resistance, and Metabolic Disease

a “Metabolic flexibility” is the ability of an organ to adapt to changes in energy demand and fuel management from fasting to fed states.

Disease Categories

...isease Categorie...

...MESSAGES: Obesity and Diabetes Mellitus The...


...10 TAKEAWAY MESSAGES: Obesity and High Blood Pr...


...nt of Adult Patients With Overweig...


...Obesity (Adiposopathy) Cause Diabetes?...


...TAKEAWAY MESSAGES: Obesity and CVD Obes...


...sopathy (“Sick Fat”) Cardiovascular Dise...


...irect Adiposopathy (“Sick Fat”) Cardiovascul...


...10 TAKEAWAY MESSAGES: Obesity and Wom...


...Y MESSAGES: Obesity and Stress Shorter-term ...


...P 10 TAKEAWAY MESSAGES: Obesity and...


...opathic Dyslipidemia: (Hypertriglyceridemia...


...ESSAGES: Obesity and MASLD MASLD h...


...0 TAKEAWAY MESSAGES: Obesity and Psychiatric D...


...MESSAGES: Obesity and Cancer Obesity is the se...


...ty Associated Cancers Head and nec...


...Factors that Increase Cancer Risks High...


...Cancer Risk Intentional weight loss among pati...


...its of Physical Activity in Patients...