Managing Adiposity-Related Diseases

Publication Date: February 28, 2024

Key Points

Key Points

  • Among the many conditions caused or worsened by excess adipose tissue (AT), the most prevalent are:
    • Cardiovascular disease (CVD)
    • Elevated blood sugar
    • High blood pressure
    • Dyslipidemia
    • Metabolic dysfunction-associated steatotic liver disease (MASLD)
    • Cancer
    • Obesity and stress: cause and effect
    • Psychiatric disease
  • These conditions are also largely improved, even prevented, by weight loss.
  • It is therefore recommended that weight loss be an integral part of management whenever excess AT accompanies any of these conditions.

Simplified Mechanism of Obesity, Insulin Resistance, and Metabolic Disease

a “Metabolic flexibility” is the ability of an organ to adapt to changes in energy demand and fuel management from fasting to fed states.

Disease Categories

Disease Categorie...

...Y MESSAGES: Obesity and Diabetes Mellitus...


...10 TAKEAWAY MESSAGES: Obesity and Hi...


...ent of Adult Patients With Overweight or Obesi...


...es Obesity (Adiposopathy) Cause Diabetes?...


...0 TAKEAWAY MESSAGES: Obesity and CVD Obesit...


...posopathy (“Sick Fat”) Cardiovasc...


...Adiposopathy (“Sick Fat”) Cardiovascular...


...EAWAY MESSAGES: Obesity and Women Obesity disp...


...0 TAKEAWAY MESSAGES: Obesity and Stre...


...AWAY MESSAGES: Obesity and Dyslipidemia The di...


...athic Dyslipidemia: (Hypertriglyceridemia, Small...


...KEAWAY MESSAGES: Obesity and MASLD...


...TAKEAWAY MESSAGES: Obesity and Psyc...


...AWAY MESSAGES: Obesity and Cancer O...


...ed Cancers Head and neck Menin...


...itional Factors that Increase Cancer Risk...


...ucing Cancer Risk Intentional we...


...ical Activity in Patients With Cancer...