Blepharitis

Publication Date: October 31, 2018
Last Updated: March 14, 2022

HIGHLIGHTED FINDINGS AND RECOMMENDATIONS FOR CARE

In the management of ocular surface disease, it is helpful to distinguish blepharitis and meibomian gland dysfunction (MGD) from aqueous deficient dry eye. Worsening of symptoms in the morning is typical of blepharitis, whereas worsening of the symptoms later in the day are typical of aqueous deficient dry eye.
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Blepharitis is typically a chronic condition that cannot be permanently cured, and successful management is dependent on patient compliance with a treatment regimen. This should be explained to the affected patient. (, , )
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Topical antibiotic ointments with or without corticosteroids or oral antibiotics can be used effectively in the treatment of blepharitis. Although azithromycin is used as a treatment for blepharitis, it may be hazardous when used orally in patients with cardiovascular problems. Specifically, oral azithromycin may lead to abnormalities in the electrical activity of the heart, with the potential to create serious irregularities in heart rhythm. (, , )
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In patients with blepharitis who do not respond to therapy, the possibility of carcinoma or immune-mediated diseases should be considered, particularly if the blepharitis is associated with a loss of eyelashes and/or conjunctival cicatricial changes. Early diagnosis and appropriate treatment can prevent disfigurement and may be lifesaving.
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Overview

Title

Blepharitis

Authoring Organization

Publication Month/Year

October 31, 2018

Last Updated Month/Year

June 9, 2022

Document Type

Guideline

External Publication Status

Published

Country of Publication

US

Document Objectives

Establish the diagnosis of blepharitis, differentiating it from other causes of irritation and redness. Identify the type of blepharitis. Establish appropriate therapy. Relieve discomfort and pain. Prevent complications. Educate and engage the patient in the management of this potentially chronic disease
 

Inclusion Criteria

Female, Male, Adolescent, Adult, Child, Older adult

Health Care Settings

Ambulatory, Emergency care, Outpatient

Intended Users

Optometrist, nurse, nurse practitioner, physician, physician assistant

Scope

Diagnosis, Management, Treatment

Diseases/Conditions (MeSH)

D001762 - Blepharitis, D005141 - Eyelid Diseases

Keywords

blepharitis, eye inflammation, eyelid swelling

Methodology

Number of Source Documents
115
Literature Search Start Date
March 1, 2017
Literature Search End Date
June 1, 2018