Pharmacologic Treatment of Chronic Insomnia in Adults

Publication Date: February 1, 2017
Last Updated: March 14, 2022

Recommendations

We suggest that clinicians use suvorexant as a treatment for sleep maintenance insomnia (versus no treatment) in adults. (Weak)
327998
We suggest that clinicians use eszopiclone as a treatment for sleep onset and sleep maintenance insomnia (versus no treatment) in adults. (Weak)
327998
We suggest that clinicians use zaleplon as a treatment for sleep onset insomnia (versus no treatment) in adults. (Weak)
327998
We suggest that clinicians use zolpidem as a treatment for sleep onset and sleep maintenance insomnia (versus no treatment) in adults. (Weak)
327998
We suggest that clinicians use triazolam as a treatment for sleep onset insomnia (versus no treatment) in adults. (Weak)
327998
We suggest that clinicians use temazepam as a treatment for sleep onset and sleep maintenance insomnia (versus no treatment) in adults. (Weak)
327998
We suggest that clinicians use ramelteon as a treatment for sleep onset insomnia (versus no treatment) in adults. (Weak)
327998
We suggest that clinicians use doxepin as a treatment for sleep maintenance insomnia (versus no treatment) in adults. (Weak)
327998
We suggest that clinicians not use trazodone as a treatment for sleep onset or sleep maintenance insomnia (versus no treatment) in adults. (Weak)
327998
We suggest that clinicians not use tiagabine as a treatment for sleep onset or sleep maintenance insomnia (versus no treatment) in adults. (Weak)
327998
We suggest that clinicians not use diphenhydramine as a treatment for sleep onset and sleep maintenance insomnia (versus no treatment) in adults. (Weak)
327998
We suggest that clinicians not use melatonin as a treatment for sleep onset or sleep maintenance insomnia (versus no treatment) in adults. (Weak)
327998
We suggest that clinicians not use tryptophan as a treatment for sleep onset or sleep maintenance insomnia (versus no treatment) in adults. (Weak)
327998
We suggest that clinicians not use valerian as a treatment for sleep onset or sleep maintenance insomnia (versus no treatment) in adults. (Weak)
327998
327998
327998

Recommendation Grading

Overview

Title

Pharmacologic Treatment of Chronic Insomnia in Adults

Authoring Organization

Publication Month/Year

February 1, 2017

Last Updated Month/Year

January 17, 2024

Supplemental Implementation Tools

Document Type

Guideline

External Publication Status

Published

Country of Publication

US

Document Objectives

The purpose of this guideline is to establish clinical practice recommendations for the pharmacologic treatment of chronic insomnia in adults, when such treatment is clinically indicated. 

Target Patient Population

Patients with chronic insomnia

Inclusion Criteria

Female, Male, Adolescent, Adult, Older adult

Health Care Settings

Ambulatory, Outpatient

Intended Users

Nurse, nurse practitioner, physician, physician assistant

Scope

Management, Treatment

Diseases/Conditions (MeSH)

D012893 - Sleep Wake Disorders, D056508 - Sleep Medicine Specialty, D000068776 - Sleep Aids, Pharmaceutical, D007319 - Sleep Initiation and Maintenance Disorders

Keywords

Insomnia, sleep disorders, chronic insomnia, suvorexant, benzodiazepine, melatonin

Supplemental Methodology Resources

Data Supplement, Data Supplement

Methodology

Number of Source Documents
175
Literature Search Start Date
April 26, 2011
Literature Search End Date
January 25, 2016