Diagnostic Accuracy Of CSF 14-3-3 Protein In Sporadic Creutzfeldt-Jakob Disease

Authoring Organization

Publication Month/Year

October 2, 2012

Document Type


External Publication Status


Country of Publication


Document Objectives

To assess the available evidence for the diagnostic accuracy of CSF testing for protein 14-3-3 in patients with suspected sporadic Creutzfeldt-Jakob disease (sCJD).

Inclusion Criteria

Female, Male, Adult, Older adult

Health Care Settings

Ambulatory, Hospice, Hospital, Outpatient


Assessment and screening, Diagnosis, Management

Diseases/Conditions (MeSH)

D007562 - Creutzfeldt-Jakob Syndrome


Creutzfeldt-Jakob disease, subacute spongiform encephalopathy, CJD

Source Citation

Evidence-based guideline: Diagnostic accuracy of CSF 14-3-3 protein in sporadic Creutzfeldt-Jakob disease. Report of the Guideline Development Subcommittee of the American Academy of Neurology. Taim Muayqil, Gary Gronseth, Richard Camicioli. Neurology Oct 2012, 79 (14) 1499-1506; DOI: 10.1212/WNL.0b013e31826d5fc3