Treatment of Restless Legs Syndrome in Adults

Authoring Organization

Publication Month/Year

November 16, 2016

Last Updated Month/Year

August 1, 2023

Supplemental Implementation Tools

Document Type


External Publication Status


Country of Publication


Document Objectives

To make evidence-based recommendations regarding restless legs syndrome (RLS) management in adults.

Inclusion Criteria

Female, Male, Adult

Health Care Settings

Ambulatory, Operating and recovery room, Outpatient

Intended Users

Nurse, nurse practitioner, physician, physician assistant



Diseases/Conditions (MeSH)

D012148 - Restless Legs Syndrome


movement disorder, restless legs syndrome, periodic limb movement disorder, RLS

Source Citation

Practice guideline summary: Treatment of restless legs syndrome in adults. Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology. John W. Winkelman, Melissa J. Armstrong, Richard P. Allen, K. Ray Chaudhuri, William Ondo, Claudia Trenkwalder, Phyllis C. Zee, Gary S. Gronseth, David Gloss, Theresa Zesiewicz. Neurology Dec 2016, 87 (24) 2585-2593; DOI: 10.1212/WNL.0000000000003388