Antibiotic Stewardship
Background
Background
Antibiotic stewardship has been defined as “coordinated interventions designed to improve and measure the appropriate use of antibiotic agents by promoting the selection of the optimal antibiotic drug regimen including dosing, duration of therapy, and route of administration.”
The benefits of antibiotic stewardship include improved patient outcomes, reduced adverse events including Clostridium difficile infection (CDI), improvement in rates of antibiotic susceptibilities to targeted antibiotics, and optimization of resource utilization across the continuum of care.
IDSA and SHEA strongly believe that antibiotic stewardship programs are best led by infectious disease physicians with additional stewardship training.
Interventions
...nterventions...
...d preauthorization and/or prospective audit...
...st relying solely on didactic educational m...
...le 1. Comparison of Preauthorizati...
...est antibiotic stewardship programs (...
...uggest ASPs implement interventions to i...
...nd antibiotic stewardship interventi...
...use of strategies (e.g., antibiotic...
...suggest incorporation of computerized clinical...
...ggest against the use of antibiotic cycling as a...
Optimization
...timizati...
...mmend that hospitals implement pharmacokinet...
...the same for vancomycin. (W - Weak, L - Low)658...
...d patients, we suggest ASPs advocate for the us...
...ecommend ASPs implement programs to increas...
...nts with a history of β-lactam allergy, w...
...d that ASPs implement guidelines and strate...
Microbiology and Laboratory Diagnostics
...ology and Laboratory Diagnostics...
...elopment of stratified antibiograms over so...
...st selective and cascade reporting of an...
We suggest the use of rapid viral testing for...
...rapid diagnostic testing in addition to...
...in ICUs with suspected infection, w...
...patients with hematologic malignan...
Measurement
Measureme...
...uggest monitoring antibiotic use as measured...
...measuring antibiotic costs based on prescript...
...asures that consider the goals and size o...
...ble 2. Possible Metrics for Evaluation of Int...
Special Populations
...ecial Populati...
...ASPs develop facility-specific guide...
...uggest implementation of ASP interventions to imp...
...n nursing homes and skilled nursing fa...
...mentation of antibiotic stewardship interventions...
...lly ill patients, we suggest ASPs...