Antibiotic Stewardship
Background
Background
Antibiotic stewardship has been defined as “coordinated interventions designed to improve and measure the appropriate use of antibiotic agents by promoting the selection of the optimal antibiotic drug regimen including dosing, duration of therapy, and route of administration.”
The benefits of antibiotic stewardship include improved patient outcomes, reduced adverse events including Clostridium difficile infection (CDI), improvement in rates of antibiotic susceptibilities to targeted antibiotics, and optimization of resource utilization across the continuum of care.
IDSA and SHEA strongly believe that antibiotic stewardship programs are best led by infectious disease physicians with additional stewardship training.
Interventions
...Interventions...
...commend preauthorization and/or prospective audi...
...suggest against relying solely on didactic...
...1. Comparison of Preauthorization an...
...uggest antibiotic stewardship programs (ASPs) deve...
...gest ASPs implement interventions to impro...
...ntibiotic stewardship interventions de...
...he use of strategies (e.g., antibiotic t...
...poration of computerized clinical deci...
...inst the use of antibiotic cycling as a ste...
Optimization
...Opt...
...hat hospitals implement pharmacokinetic...
...e same for vancomycin. (W - Weak, L -...
...patients, we suggest ASPs advocate for the us...
...mend ASPs implement programs to increase bo...
...tients with a history of β-lactam allergy, we su...
...recommend that ASPs implement guid...
Microbiology and Laboratory Diagnostics
...Microbiology a...
...development of stratified antibiograms over...
...selective and cascade reporting of a...
...gest the use of rapid viral testing for respi...
...ggest rapid diagnostic testing in...
...Us with suspected infection, we suggest the use of...
...with hematologic malignancy at risk...
Measurement
...M...
...uggest monitoring antibiotic use as measured by d...
...nd measuring antibiotic costs based...
...s that consider the goals and size of t...
...2. Possible Metrics for Evaluation of Interven...
Special Populations
...Spec...
...suggest ASPs develop facility-specifi...
...t implementation of ASP interventio...
...mes and skilled nursing facilities,...
...mplementation of antibiotic stewardshi...
...terminally ill patients, we suggest ASPs...