Antibiotic Stewardship

Publication Date: April 13, 2016

Background

Background

Approaches to optimize the use of both existing antibiotics and newly developed antibiotics are of critical importance to ensure that we continue to reap their benefits and provide the best care to patients.

Antibiotic stewardship has been defined as “coordinated interventions designed to improve and measure the appropriate use of antibiotic agents by promoting the selection of the optimal antibiotic drug regimen including dosing, duration of therapy, and route of administration.”

The benefits of antibiotic stewardship include improved patient outcomes, reduced adverse events including Clostridium difficile infection (CDI), improvement in rates of antibiotic susceptibilities to targeted antibiotics, and optimization of resource utilization across the continuum of care.

IDSA and SHEA strongly believe that antibiotic stewardship programs are best led by infectious disease physicians with additional stewardship training.

Interventions

...rventions...

...ecommend preauthorization and/or pr...


...inst relying solely on didactic educ...


...1. Comparison of Preauthorization and Prospective...


...suggest antibiotic stewardship programs (ASPs)...


We suggest ASPs implement interventions...


...ecommend antibiotic stewardship interve...


...suggest the use of strategies (e.g., antibiot...


...incorporation of computerized clinical de...


...suggest against the use of antibiotic cycling as...


Optimization

...timizatio...

...t hospitals implement pharmacokinetic monitorin...


...nd suggest the same for vancomycin. (W - Weak, L -...


...ed patients, we suggest ASPs advocate for...


...recommend ASPs implement programs to increase bo...


...ients with a history of β-lactam aller...


...that ASPs implement guidelines and strategies...


Microbiology and Laboratory Diagnostics

...biology and Laboratory Diagnostics

We suggest development of stratified...


We suggest selective and cascade rep...


We suggest the use of rapid viral t...


...st rapid diagnostic testing in additi...


...ults in ICUs with suspected infection,...


...with hematologic malignancy at risk o...


Measurement

...asuremen...

...st monitoring antibiotic use as measured by day...


...suring antibiotic costs based on p...


...consider the goals and size of the syndrome-s...


...e 2. Possible Metrics for Evaluation o...


Special Populations

...l Populations...

...ASPs develop facility-specific guide...


...ementation of ASP interventions to improve t...


...es and skilled nursing facilities, we sugge...


...ggest implementation of antibiotic stew...


...ill patients, we suggest ASPs provide supp...