Antibiotic Stewardship
Background
Background
Antibiotic stewardship has been defined as “coordinated interventions designed to improve and measure the appropriate use of antibiotic agents by promoting the selection of the optimal antibiotic drug regimen including dosing, duration of therapy, and route of administration.”
The benefits of antibiotic stewardship include improved patient outcomes, reduced adverse events including Clostridium difficile infection (CDI), improvement in rates of antibiotic susceptibilities to targeted antibiotics, and optimization of resource utilization across the continuum of care.
IDSA and SHEA strongly believe that antibiotic stewardship programs are best led by infectious disease physicians with additional stewardship training.
Interventions
...erventions...
...nd preauthorization and/or prospective au...
...nst relying solely on didactic educati...
...omparison of Preauthorization and Prospective...
...antibiotic stewardship programs (ASPs) develo...
...s implement interventions to improve...
...ecommend antibiotic stewardship interventions d...
...he use of strategies (e.g., antibiotic time-out...
...e suggest incorporation of computerized clin...
...ainst the use of antibiotic cycling as a stewards...
Optimization
Optimizati...
...mend that hospitals implement pharmacokinetic...
...same for vancomycin. (W - Weak, L -...
...spitalized patients, we suggest ASPs advocate for...
...SPs implement programs to increase both appropriat...
...ents with a history of β-lactam allergy,...
...ommend that ASPs implement guidelines and strate...
Microbiology and Laboratory Diagnostics
...crobiology and Laboratory Diagnost...
...est development of stratified antibiograms over s...
...selective and cascade reporting of a...
...suggest the use of rapid viral testing for respir...
We suggest rapid diagnostic testing...
...CUs with suspected infection, we suggest the...
...th hematologic malignancy at risk of contract...
Measurement
...asurement...
...oring antibiotic use as measured by days of...
...end measuring antibiotic costs based on...
...ures that consider the goals and siz...
...Possible Metrics for Evaluation of Intervention...
Special Populations
...pecial Popula...
...SPs develop facility-specific guid...
...ementation of ASP interventions to improve th...
...rsing homes and skilled nursing facilities...
...mplementation of antibiotic stewardship interve...
...y ill patients, we suggest ASPs provide support to...