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Chronic Pancreatitis
Publication Date: February 1, 2020
Last Updated: March 14, 2022
Recommendations
Diagnosis of CP
1. We recommend CTor MRI for the first-line diagnosis of CP. Either test should be the first choice for the diagnosis of CP. Endoscopic ultrasonography (EUS), because of its invasiveness and lack of specificity, should be used only if the diagnosis is in question after cross-sectional imaging is performed. (Strong “We recommend”, Low)
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2. We suggest performing secretin-enhanced magnetic resonance cholangiopancreatography (s-MRCP) when the diagnosis of CP following cross-sectional imaging or EUS is not confirmed and the clinical suspicion remains high. (Conditional (weak) “We suggest”, Low)
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3. We suggest histological examination as the gold standard to diagnose CP in high-risk patients when the clinical and functional evidence of CP is strong, but imaging modalities are inconclusive. (Conditional (weak) “We suggest”, Very low)