Treatment of Extended Spectrum β-lactamase Producing Enterobacterales (ESBL-E), Carbapenem-Resistant Enterobacterales (CRE), and Pseudomonas aeruginosa with Difficult-to-Treat Resistance (DTRP. aeruginosa)

Document Overview

Document Title

Treatment of Extended Spectrum β-lactamase Producing Enterobacterales (ESBL-E), Carbapenem-Resistant Enterobacterales (CRE), and Pseudomonas aeruginosa with Difficult-to-Treat Resistance (DTRP. aeruginosa)

Authoring Society

Infectious Diseases Society of America

Document Publication Date

Apr 19, 2022

Page Last Reviewed/Updated

May 5, 2026

Document Type

Consensus Statement

Country of Publication

United States

Full Text Freely Available

Yes

Full Text Guideline

academic.oup.com/cid/advance-article/doi/10.1093/cid/ciac268/6570801

Source Citation

Tamma PD, Aitken SL, Bonomo RA, Mathers AJ, van Duin D, Clancy CJ. Infectious Diseases Society of America 2022 Guidance on the Treatment of Extended-Spectrum β-lactamase Producing Enterobacterales (ESBL-E), Carbapenem-Resistant Enterobacterales (CRE), and Pseudomonas aeruginosa with Difficult-to-Treat Resistance (DTR-P. aeruginosa). Clin Infect Dis. 2022 Apr 19:ciac268. doi: 10.1093/cid/ciac268. Epub ahead of print. PMID: 35439291.

Supplemental Implementation Resources

• Quick-Reference Guide

Document Scope, Criteria, and Use Cases

Scope

Management

Diseases/Conditions (MeSH)

D006090 - Gram-Negative Bacteria

D016905 - Gram-Negative Bacterial Infections

D006090 - Gram-Negative Bacteria

D016905 - Gram-Negative Bacterial Infections

Keywords

Antibiotic Resistance, Carbapenem-Resistant Enterobacterales, antibiotics, gram-negative

Inclusion Criteria

Male, Female, Adolescent, Adult, Child, Infant

Health Care Settings

Ambulatory, Hospital, Outpatient

Intended Users

Nurse, Nurse Practitioner, Physician, Physician Assistant

Recommendation Development Processes & Methodology

Number of Source Documents

349

Includes peer/external review process?

Yes

Includes public comment process?

No

Methodologist involvement?

Yes

Patient involvement?

No

Includes multi-disciplinary group?

Yes

Includes systematic review?

Yes

Grades quality of strength of evidence?

No

Grades quality of strength of recommendation?

No

Discloses funding source?

Yes

Discloses conflicts of interest?

Yes

Includes benefits/harms analysis with recommendations?

No