Routine Lung Function Tests

Publication Date: December 22, 2021

Key Points

Key Points

  • Interpretation of pulmonary function tests (PFTs) must take into account a level of uncertainty relating to:
    1. how representative the obtained result was of the individual’s lung function at the time of testing,
    2. how the pre-test probability of disease may influence what is the appropriate threshold for that individual, and
    3. how valid for the individual the reference population is against which the test is being judged.
  • In the future it may also be reasonable to set clinical decision-making thresholds for a test based on clinical risk and observed clinical outcomes.
  • A more comprehensive approach to interpretation (not simply relying on whether results are within or outside the normal range) is imperative for appropriate interpretation of lung function when pre-screening for employment, for tracking the effects of exposure, for disability assessment, and for risk assessment for therapies potentially toxic to the lungs.
  • The interpretation of PFT results must always consider the inherent biological variability of the tests and the uncertainty of the test result.

Interpretation

...terpretation

...Global Lung Function Initiative (GLI) reference...


...x 1. Determination of a Bronchodilator Resp...


...ed data to support a single recommendati...


...lation of a Conditional Change Sco...


.... Calculation of FEV1Q in adultsFE...


Figures

...igures...

...Normal Distribution With Z-scores and...


...VC Predicted and Limits of Normal...


...omparison of the ATS/ERS 2005 Recommen...


...ples of Typical Flow-Volume Loop Configurations...


...gure 5. Approach to Interpretation of Sp...


Classification of Ventilatory Impairments Define...


.... Approach to Interpretation of DLCO...


...proach to Interpretation of Lung Vo...


...on of Ventilatory Impairments Defined by Lung...


Tables

Table...

...le 1. Functional Classification of Common Impair...


Table 2. Summary of Types of Spirometricall...


...le 3. Lung Function Indices Capable o...