Last updated March 14, 2022

Treatment of Low Bone Density or Osteoporosis to Prevent Fractures in Men and Women

Recommendations

ACP recommends that clinicians offer pharmacologic treatment with alendronate, risedronate, zoledronic acid, or denosumab to reduce the risk for hip and vertebral fractures in women who have known osteoporosis. (SH)
565

ACP recommends that clinicians treat osteoporotic women with pharmacologic therapy for 5 years. (WL)
565

ACP recommends that clinicians offer pharmacologic treatment with bisphosphonates to reduce the risk for vertebral fracture in men who have clinically recognized osteoporosis. (WL)
565

ACP recommends against bone density monitoring during the 5-year pharmacologic treatment period for osteoporosis in women. (WL)
565

ACP recommends against using menopausal estrogen therapy or menopausal estrogen plus progestogen therapy or raloxifene for the treatment of osteoporosis in women. (SM)
565

ACP recommends that clinicians should make the decision whether to treat osteopenic women 65 years of age or older who are at a high risk for fracture based on a discussion of patient preferences, fracture risk profile, and benefits, harms, and costs of medications. (WL)
565

Recommendation Grading

Overview

Title

Treatment of Low Bone Density or Osteoporosis to Prevent Fractures in Men and Women

Authoring Organization

Endorsing Organization

Publication Month/Year

June 6, 2017

Document Type

Guideline

External Publication Status

Published

Country of Publication

US

Inclusion Criteria

Female, Male, Adult, Older adult

Health Care Settings

Ambulatory, Hospital, Outpatient

Intended Users

Physician assistant, physician, occupational therapist, nurse, nurse practitioner

Scope

Prevention, Management, Treatment

Diseases/Conditions (MeSH)

D010024 - Osteoporosis, D058866 - Osteoporotic Fractures

Keywords

osteoporosis, Osteoporosis, low bone density, bone fractures, fracture prevention

Methodology

Number of Source Documents
387
Literature Search Start Date
January 2, 2005
Literature Search End Date
June 3, 2011