Screening for Colorectal Cancer in Asymptomatic Average-Risk Adults

Publication Date: November 5, 2019

Guidance Statements

Clinicians should screen for colorectal cancer in average-risk adults between the ages of 50 and 75 years.
Clinicians should select the colorectal cancer screening test with the patient on the basis of a discussion of benefits, harms, costs, availability, frequency, and patient preferences. Suggested screening tests and intervals are fecal immunochemical testing or high-sensitivity guaiac-based fecal occult blood testing every 2 years, colonoscopy every 10 years, or flexible sigmoidoscopy every 10 years plus fecal immunochemical testing every 2 years.
Clinicians should discontinue screening for colorectal cancer in average-risk adults older than 75 years or in adults with a life expectancy of 10 years or less.

Recommendation Grading




Screening for Colorectal Cancer in Asymptomatic Average-Risk Adults

Authoring Organization

Publication Month/Year

November 5, 2019

Document Type


External Publication Status


Country of Publication


Document Objectives

The purpose of this guidance statement is to guide clinicians on colorectal cancer screening in average-risk adults.

Inclusion Criteria

Female, Male, Adult, Older adult

Health Care Settings

Ambulatory, Hospital, Radiology services

Intended Users

Radiology technologist, psychologist, counselor, nurse, nurse practitioner, physician, physician assistant


Assessment and screening, Prevention

Diseases/Conditions (MeSH)

D015179 - Colorectal Neoplasms


colorectal cancer, cancer screening, preventative care

Supplemental Methodology Resources

Data Supplement, Data Supplement


Number of Source Documents
Literature Search Start Date
June 1, 2014
Literature Search End Date
May 28, 2018