Design and created by Guideline Central in participation with the American Psychiatric Association.

American Psychiatric Association
Publication Date: February 14, 2023
| Y / N | Do you make yourself Sick because you feel uncomfortably full? |
| Y / N | Do you worry you have lost Control over how much you eat? |
| Y / N | Have you recently lost >14 lbs (One stone) in a 3-month period? |
| Y / N | Do you believe yourself to be Fat when others say you are too thin? |
| Y / N | Would you say that Food dominates your life? |
| Y / N | To assess for binge eating disorder, add: During the last 3 months, did you have any episodes of excessive overeating (i.e., eating significantly more than what most people would eat in a similar period of time)? |
| Y / N | Do you often feel the desire to eat when you are emotionally upset or stressed? |
| Y / N | Do you often feel that you can’t control what or how much you eat? |
| Y / N | Do you sometimes make yourself throw up (vomit) to control your weight? |
| Y / N | Are you often preoccupied with a desire to be thinner? |
| Y / N | Do you believe yourself to be fat when others say you are too thin? |
| Y / N | Are you satisfied with your eating patterns? Answering “no” to this question is classified as an abnormal response. |
| Y / N | Do you ever eat in secret? Answering “yes” to this and all other questions is classified as an abnormal response. |
| Y / N | Does your weight affect the way you feel about yourself? |
| Y / N | Have any members of your family suffered with an eating disorder? |
| Y / N | Do you make yourself sick because you feel uncomfortably full? |
| Related to nutritional restriction | Related to purging |
|---|---|
| Low weight, cachexia | |
| Fatigue | |
| Weakness | Weakness |
| Dehydration | |
| Cold intolerance, low body temperature | |
| Hot flashes, sweating |
| Related to nutritional restriction | Related to purging |
|---|---|
| Anxiety, depression, or irritability | Anxiety, depression, or irritability |
| Apathy | Apathy |
| Poor concentration | Poor concentration |
| Headache | Headache |
| Seizures (in severe cases) | Seizures (in severe cases) |
| Paresthesia (due to electrolyte abnormalities) | |
| Peripheral polyneuropathy (in severe cases) |
| Related to nutritional restriction | Related to purging |
|---|---|
| Dysphagia | |
| Dental enamel erosion and decay | |
| Enlarged salivary glands | |
| Pharyngeal pain | |
| Palatal scratches, erythema, or petechiae |
| Related to nutritional restriction | Related to purging |
|---|---|
| Abdominal discomfort | Abdominal discomfort |
| Constipation | Constipation |
| Diarrhea (due to laxative use) | |
| Nausea | |
| Early satiety | |
| Abdominal distention, bloating | Abdominal distention, bloating |
| Heartburn, gastroesophageal erosions or inflammation | |
| Vomiting, possibly bloodstreaked | |
| Rectal prolapse |
| Related to nutritional restriction | Related to purging |
|---|---|
| Dizziness, faintness, orthostatic hypotension | Dizziness, faintness, orthostatic hypotension |
| Palpitations, arrhythmias | Palpitations, arrhythmias |
| Bradycardia | |
| Weak irregular pulse | |
| Cold extremities, acrocyanosis | |
| Chest pain | |
| Dyspnea |
| Related to nutritional restriction | Related to purging |
|---|---|
| Slowing of growth (in children or adolescents) | Slowing of growth (in children or adolescents) |
| Arrested development of secondary sex characteristics | Arrested development of secondary sex characteristics |
| Low libido | Low libido |
| Fertility problems | |
| Oligomenorrhea | Oligomenorrhea |
| Primary or secondary amenorrhea |
| Related to nutritional restriction | Related to purging |
|---|---|
| Proximal muscle weakness, wasting, or atrophy | |
| Muscle cramping | |
| Bone pain2 | Bone pain2 |
| Stress fractures2 | Stress fractures2 |
| Slowed growth (relative to expected)2 | Slowed growth (relative to expected)2 |
| Related to nutritional restriction | Related to purging |
|---|---|
| Dry, yellow skin | |
| Change in hair including hair loss and dry and brittle hair | |
| Lanugo | |
| Scarring on dorsum of hand (Russell's sign) | |
| Poor skin turgor | Poor skin turgor |
| Pitting edema (with refeeding) | Pitting edema |
| Recommendation | Organ system | Test | Related to nutritional restriction | Related to purging |
|---|---|---|---|---|
| Recommended | Cardiovascular | ECG | Bradycardia or arrhythmias, QTc prolongation | Increased P-wave amplitude and duration, increased PR interval, widened QRS complex, QTc prolongation, ST depression, T-wave inversion or flattening, U waves, supraventricular or ventricular tachyarrhythmias |
| Recommended | Metabolic | Serum electrolytes | Hypokalemia, hyponatremia, hypomagnesemia, hypophosphatemia (especially on refeeding) | Hypokalemia, hyponatremia, hypochloremia, hypomagnesemia, hypophosphatemia, metabolic acidosis |
| Recommended | Metabolic | Lipid panel | Hypercholesterolemia | |
| Recommended | Metabolic | Serum glucose | Low blood sugar | |
| Recommended | Gastrointestinal | Liver function and associated tests | Elevated liver function tests | |
| Recommended | Genitourinary | Renal function tests | Increased BUN, decreased GFR, decreased Cr because of low lean body mass (normal Cr may indicate azotemia), renal failure (rare) | Increased BUN and Cr, renal failure (rare) |
| Based on history or exam | Genitourinary | Urinalysis | Urinary specific gravity abnormalities | Urinary specific gravity abnormalities, high pH |
| Based on history or exam | Reproductive | Serum gonadotropins and sex hormones | Decreased serum estrogen or serum testosterone; prepubertal patterns of luteinizing hormone, follicle stimulating hormone secretion | May be hypoestrogenemic if menstrual irregularities are present |
| Based on history or exam | Skeletal | Bone densitometry (DXA scan) | Reduced BMD, osteopenia, or osteoporosis in individuals with previous low weight and menstrual irregularity or amenorrhea | Reduced BMD, osteopenia or osteoporosis in individuals with previous low weight and menstrual irregularity or amenorrhea |
| Incidental | Oropharyngeal | Dental radiography | Erosion of dental enamel |
| Factor | Adults | Adolescents (12–19 years) |
|---|---|---|
| Heart rate | <50 bpm | <50 bpm |
| Orthostatic change in heart rate | Sustained increase of >30 bpm | Sustained increase of >40 bpm |
| Blood pressure | <90/60 mmHg | <90/45 mmHg |
| Orthostatic blood pressure | >20 mmHg drop in sBP | >20 mmHg drop in sBP |
| Glucose | <60 mg/dL | <60 mg/dL |
| Potassium | Hypokalemia1 | Hypokalemia1 |
| Sodium | Hyponatremia1 | Hyponatremia1 |
| Phosphate | Hypophosphatemia1 | Hypophosphatemia1 |
| Magnesium | Hypomagnesemia1 | Hypomagnesemia1 |
| Temperature | <36° C (<96.8° F) | <36° C (<96.8° F) |
| BMI | <15 | <75% of median BMI for age and sex |
| Rapidity of weight change | >10% weight loss in 6 months or >20% weight loss in 1 year | >10% weight loss in 6 months or >20% weight loss in 1 year |
| Compensatory behaviors | Occur frequently and have either caused serious physiological consequences or not responded to treatment at a lower level of care | Occur frequently and have either caused serious physiological consequences or not responded to treatment at a lower level of care |
| ECG | Prolonged QTc >450 or other significant ECG abnormalities | Prolonged QTc >450 or other significant ECG abnormalities |
| Other conditions | Acute medical complications of malnutrition (e.g., seizures, syncope, cardiac failure, pancreatitis) | Acute medical complications of malnutrition (e.g., seizures, syncope, cardiac failure, pancreatitis), arrested growth and development |
| Level of care | Unit security | Patient legal status |
|---|---|---|
| Specialized pediatric/ medical inpatient eating disorders program | Unlocked | Voluntary or involuntary |
| General pediatric/ medical inpatient program | Unlocked | Voluntary |
| Specialized psychiatric inpatient eating disorders program | Typically locked | Voluntary or involuntary |
| General psychiatric inpatient program | Typically locked | Voluntary or involuntary |
| Residential program | Unlocked | Voluntary |
| Partial hospital | Unlocked | Voluntary |
| Intensive outpatient | Unlocked | Voluntary |
| Outpatient | Unlocked | Voluntary |
| Level of care | Physician on-site 24/7 | Nursing on-site 24/7 | Medical monitoring |
|---|---|---|---|
| Specialized pediatric/ medical inpatient eating disorders program | On-site 24/7 | On-site 24/7 | Frequent |
| General pediatric/ medical inpatient program | On-site 24/7 | On-site 24/7 | Frequent |
| Specialized psychiatric inpatient eating disorders program | On-call or on-site 24/7 | On-site 24/7 | Frequent |
| General psychiatric inpatient program | On-call or on-site 24/7 | On-site 24/7 | Frequent |
| Residential program | On-call 24/7 | Typically on-site 24/7 | Limited |
| Partial hospital | Typically not on-site full-time | Typically not on-site full-time | Limited |
| Intensive outpatient | Not on-site full-time | Typically not on-site | Limited |
| Outpatient | No | No | As indicated |
| Level of care | Hours of operation | Able to maintain work/school |
|---|---|---|
| Specialized pediatric/ medical inpatient eating disorders program | 24/7 | School, in some instances |
| General pediatric/ medical inpatient program | 24/7 | School, in some instances |
| Specialized psychiatric inpatient eating disorders program | 24/7 | School, in some instances |
| General psychiatric inpatient program | 24/7 | School, in some instances |
| Residential program | 24/7 | School, in some instances |
| Partial hospital | Variable hours per day (5–12 hours) and days per week (5–7) | School, in some instances |
| Intensive outpatient | 3–4 hours per day, 3–7 days per week | Often |
| Outpatient | 1–2 psychotherapy sessions per week with additional visits with other clinicians as indicated | Yes |
| Level of care | Option for IV hydration | Option for nasogastric tube feedings | Meal supervision and support | Nutritional management |
|---|---|---|---|---|
| Specialized pediatric/ medical inpatient eating disorders program | Yes | Yes | All meals/day | Yes |
| General pediatric/ medical inpatient program | Yes | Yes | In some instances | Consultation |
| Specialized psychiatric inpatient eating disorders program | On some units | On some units | All meals/day | Yes |
| General psychiatric inpatient program | On some units | On some units | Not eating disorder-specific | Consultation |
| Residential program | No | Typically not | All meals/day | Yes |
| Partial hospital | No | No | 2–3 meals/day | Yes |
| Intensive outpatient | No | No | ~1 meal/day | Variable |
| Outpatient | No | No | Provided by family or care partners | As indicated |
| Level of care | Option for treatment over objection | Medical management | Psychiatric management | Psychological management | Multi-disciplinary team-based management |
|---|---|---|---|---|---|
| Specialized pediatric/ medical inpatient eating disorders program | Yes | Yes | Yes | Yes | Yes |
| General pediatric/ medical inpatient program | Yes | Yes | Consultation | In some instances | In some instances, not eating disorder specific |
| Specialized psychiatric inpatient eating disorders program | Yes | Consultation | Yes | Yes | Yes |
| General psychiatric inpatient program | Yes | Consultation | Not eating disorder specific | On some units, not eating disorder specific | Not eating disorder specific |
| Residential program | No | Limited consultation | Yes | Yes | Yes |
| Partial hospital | No | Limited consultation | Yes | Yes | Yes |
| Intensive outpatient | No | No | Variable | Yes | Yes |
| Outpatient | No | Outpatient, as indicated | As indicated | Yes | As indicated |
| Level of care | Group-based therapies | Individual psychotherapies | Family psychotherapies | Milieu therapy |
|---|---|---|---|---|
| Specialized pediatric/ medical inpatient eating disorders program | Yes | Yes | Yes | Yes |
| General pediatric/ medical inpatient program | No | Generally not available | Generally not available | No |
| Specialized psychiatric inpatient eating disorders program | Yes | Yes | On some units | Yes |
| General psychiatric inpatient program | Not eating disorder specific | Not eating disorder specific | Not eating disorder specific | Not eating disorder specific |
| Residential program | Yes | Yes | Yes | Yes |
| Partial hospital | Yes | Yes | Yes | Yes |
| Intensive outpatient | Yes | Yes | Yes | Yes |
| Outpatient | As indicated | Yes | Yes | No |
| Component | CBT-AN | CBT-E | FPT | SSCM | MANTRA | ECHO | AFT | FBT |
|---|---|---|---|---|---|---|---|---|
| In-session weighing | × | × | × | × | × | |||
| Individualized case formulation | × | × | × | × | × | × | ||
| Motivational phase of treatment | × | × | × | × | × | × | ||
| Focus on interpersonal issues/emotional expression | × | × | × | × | × | × | × | (indirectly) |
| Monitoring of symptoms, including eating | × | × | × | × | × | × | × | × |
| Examining association of symptoms/eating with cognitions | × | × | ||||||
| Focus on building activities/passions to minimize overconcern with weight/body shape | × | × | If raised by patient | × | × | |||
| Use of an experimental mindset to change attitudes and behaviors | × | × | × | × | ||||
| Parent-facilitated meal supervision | × | × |
| Grade | Description |
| 1 | Recommendation: indicates confidence that the benefits of the intervention clearly outweigh harms. |
| 2 | Suggestion: indicates greater uncertainty: although the benefits of the statement are still viewed as outweighing the harms, balance of benefits and harms is more difficult to judge, or the benefits or the harms may be less clear. With a suggestion, patient values and preferences may be more variable, and this can influence the clinical decision that is ultimately made. |
| Grade | Strength of Evidence |
| A | High: high confidence that the evidence reflects the true effect. Further research is very unlikely to change our confidence in the estimate of effect. |
| B | Moderate: moderate confidence that the evidence reflects the true effect. Further research may change our confidence in the estimate of effect and may change the estimate. |
| C | Low: low confidence that the evidence reflects the true effect. Further research is likely to change our confidence in the estimate of effect and is likely to change the estimate. |
American Psychiatric Association: Practice Guideline for the Treatment of Patients with Eating Disorders, Fourth Edition. Washington, DC, American Psychiatric Publishing 2023.
This resource is for informational purposes only, intended as a quick-reference tool based on the cited source guideline(s), and should not be used as a substitute for the independent professional judgment of healthcare providers. Practice guidelines are unable to account for every individual variation among patients or take the place of clinician judgment, and the ultimate decision concerning the propriety of any course of conduct must be made by healthcare providers after consideration of each individual patient situation. Guideline Central does not endorse any specific guideline(s) or guideline recommendations and has not independently verified the accuracy hereof. Any use of this resource or any other Guideline Central resources is strictly voluntary. The most common U.S. trade names are included for reference only. At the time of publication, some of these products may be manufactured only as generic products. Other medications or other formulations of the listed medications may be available in Canada. The review of the content included in this Pocket Guide was funded in part by the Gordon and Betty Moore Foundation through a grant program administered by the Council of Medical Specialty Societies.
Guideline Central and select third party use “cookies” on this website to enhance the user experience.
This technology helps us gather statistical and analytical information to optimize the relevant content for you.
The user also has the option to opt-out which may have an effect on the browsing experience.