Coagulation Disorders in Patients With Cirrhosis

Publication Date: September 24, 2021

Key Points

Key Points

  • Significant alterations in laboratory parameters — such as platelet count (PLT) and prothrombin time/international normalized ratio (PT/INR) — routinely accompany cirrhosis.
    • However, the risks of both bleeding and thrombosis are not accurately quantitated by standard testing in this population.
  • The best strategies to identify patients at risk for bleeding or thrombosis, to provide appropriate prophylaxis in patients at risk for clinically significant bleeding, to screen for and treat portal vein thrombosis, and to prevent clinically significant thromboembolic events are currently unknown.

Diagnosis

...Diagnosis...

...Te...

...o-elastic Testing (VET)In patients with sta...

...n patients with stable cirrhosis (...


...Portal Vein...

...with cirrhosis, the AGA suggests against...


Treatment

...Treatment...

Preprocedur...

...Fresh Frozen Plasma (FFP)In patients with stable...

...mbopoietin receptor agonist (TPO-Ras)In pati...


...Venous Throm...

...lized patients with cirrhosis and who otherwise me...


...Acut...

...tients with cirrhosis and acute or s...


...Atrial Fibrilla...

...s with cirrhosis and atrial fibrillation with...


...cedure Risk StratificationHaving trouble vie...