Document Overview

Document Title

Diagnosis and Management of Aortic Disease

Authoring Societies

American College of Cardiology

American Heart Association

Document Publication Date

Nov 1, 2022

Page Last Reviewed/Updated

May 5, 2026

Document Type

Guideline

Country of Publication

United States

Full Text Freely Available

Yes

Full Text Guideline

www.jacc.org/guidelines/aortic-disease

Source Citation

Isselbacher EM, Preventza O, Black JH III, Augoustides JG, Jones WS, Beck AW, Kalahasti, Bolen MA, Kim KM, Braverman AC, Milewicz DM, Bray BE, Oderich GS, Brown-Zimmerman MM, Ogbechie L, Chen EP, Promes SB, Collins TJ, Ross EG, DeAnda Jr A, Schermerhorn ML, Fanola CL, Times SS, Girardi LN, Tseng EE, Hicks CW, Wang GJ, Hui DS, Woo YJ, Beckman JA, Otto CM, O’Gara PT, Armbruster A, Jones WS, Birtcher KK, Mark D, de las Fuentes L, Mukherjee D, Deswal A, Palaniappan L, Dixon DL, Piano MR, Gorenek B, Rab T, Haynes N, Spatz ES, Hernandez AF, Tamis-Holland JE, Joglar JA. 2022 AHA/ACC Guideline for the Diagnosis and Management of Aortic Disease: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines[published online ahead of print November 2, 2022]. J Am Coll Cardiol. doi: 10.1016/j.jacc.2022.08.004.
Copublished in Circulation. doi: 10.1161/CIR.0000000000001106.

Supplemental Implementation Resources

• Decision Aid
• Slide Set
• Patient Information
• CME
• Visual Abstract
• Patient Information

Document Scope, Criteria, and Use Cases

Document Objectives

Guide clinicians in the diagnosis, genetic evaluation and family screening, medical therapy, endovascular and surgical treatment, and long-term surveillance of patients with aortic disease across its multiple clinical presentation subsets (ie, asymptomatic, stable symptomatic, and acute aortic syndromes).

Scope

Assessment and Screening, Counseling, Diagnosis, Management, Prevention, Rehabilitation, Treatment

Diseases/Conditions (MeSH)

D001018 - Aortic Diseases

D065467 - Transcatheter Aortic Valve Replacement

D001019 - Aortic Rupture

D017544 - Aortic Aneurysm, Abdominal

D001014 - Aortic Aneurysm

D017545 - Aortic Aneurysm, Thoracic

D001015 - Aortic Arch Syndromes

D000783 - Aneurysm

D008382 - Marfan Syndrome

D017542 - Aneurysm, Ruptured

D013700 - Giant Cell Arteritis

D013625 - Takayasu Arteritis

D001017 - Aortic Coarctation

D000082882 - Bicuspid Aortic Valve Disease

D014424 - Turner Syndrome

D055947 - Loeys-Dietz Syndrome

D004535 - Ehlers-Danlos Syndrome

D000784 - Aneurysm, Dissecting

D000785 - Aneurysm, Infected

D001018 - Aortic Diseases

D065467 - Transcatheter Aortic Valve Replacement

D001019 - Aortic Rupture

D017544 - Aortic Aneurysm, Abdominal

D001014 - Aortic Aneurysm

D017545 - Aortic Aneurysm, Thoracic

D001015 - Aortic Arch Syndromes

D000783 - Aneurysm

D008382 - Marfan Syndrome

D017542 - Aneurysm, Ruptured

D013700 - Giant Cell Arteritis

D013625 - Takayasu Arteritis

D001017 - Aortic Coarctation

D000082882 - Bicuspid Aortic Valve Disease

D014424 - Turner Syndrome

D055947 - Loeys-Dietz Syndrome

D004535 - Ehlers-Danlos Syndrome

D000784 - Aneurysm, Dissecting

D000785 - Aneurysm, Infected

Keywords

ACTA2, Aberrant Subclavian Artery, BGN, Bicuspid aortic valve, Bovine Arch, Coarctation of the aorta, FLNA, Infectious aortitis, Inflammatory aortitis, Kommerell’s diverticulum, LOX, Loeys-Dietz syndrome, MYH11, MYLK, Marfan Syndrome, Multidisciplinary Aortic Team, PRKG1, Smooth muscle dysfunction syndrome, Takayasu arteritis, Thoracoabdominal Aortic Aneurysm, Turner syndrome, Vascular Ehlers-Danlos syndrome, abdominal aortic aneurysm, aneurysm, aortic aneurysm, aortic disease, aortic dissection, aortic imaging, aortic repair, aortic root replacement surgery, aortic rupture, aortic surgery, atherosclerosis, congenital heart defects, endovascular repair, fetal maternal medicine, giant cell arteritis, hypertension, pregnancy, pregnancy complication, surgical aortic valve replacement, thoracic aortic aneurysm, thoracic aortic aneurysms, thoracic endovascular aortic repair, transcatheter aortic valve replacement (TAVR), traumatic aortic injury, type A aortic dissection, type b aortic dissection

Target Patient Population

Patients with aortic disease across its multiple clinical presentation subsets

Inclusion Criteria

Male, Female, Adolescent, Adult, Child, Older Adult

Health Care Settings

Ambulatory, Emergency Care, Hospital, Radiology Services

Intended Users

Nurse, Nurse Practitioner, Physician, Physician Assistant

Recommendation Development Processes & Methodology

Supplemental Methodology Resources

Data Supplement Systematic Review Document

Number of Source Documents

1,457

Literature Search Start Date

Wednesday, March 31, 2021

Literature Search End Date

Tuesday, May 31, 2022

Includes peer/external review process?

Yes

Includes public comment process?

No

Methodologist involvement?

Yes

Patient involvement?

No

Includes multi-disciplinary group?

Yes

Includes systematic review?

Yes

Grades quality of strength of evidence?

Yes

Grades quality of strength of recommendation?

Yes

Discloses funding source?

Yes

Discloses conflicts of interest?

Yes

Includes benefits/harms analysis with recommendations?

Yes