Management of Pregnancy

We recommend offering non-invasive prenatal testing as the prenatal screening test of choice for all patients with singleton pregnancies who choose aneuploidy screening. (Strong for)

We suggest non-invasive prenatal testing for patients with twin pregnancies who choose aneuploidy screening. (Weak for)

We recommend considering fetal fibronectin testing as a part of the evaluation strategy in patients between 24 0/7 and 34 6/7 weeks’ gestation with signs and symptoms of preterm labor, particularly in facilities where the result might affect management of delivery. (Strong for)

We suggest vaginal progesterone or cerclage for singleton pregnancy with short cervix, history of spontaneous preterm birth, or both depending on patient characteristics and preferences. (Weak for)

There is insufficient evidence to recommend for or against the use of aspirin to reduce recurrent spontaneous preterm birth. (Neither for or against)