Management of Primary Cutaneous Melanoma

Publication Date: November 1, 2018
Last Updated: March 14, 2022


Diagnostic biopsy of suspected melanoma

Preferred biopsy technique is a narrow excisional/ complete biopsy with 1- to 3-mm margins that encompass the entire breadth of lesion and is of sufficient depth to prevent transection at the base. This may be accomplished by fusiform/elliptical or punch excision or deep shave/saucerization removal to depth below the anticipated plane of the lesion. (B)

AAD, American Academy of Dermatology; AJCC, American Joint Committee on Cancer; BRAFI, B-Raf proto-oncogene serine/threonine kinase inhibitor; CGH, comparative genomic hybridization; CLND, completion lymph node dissection; CM, cutaneous melanoma; CM, cutaneous melanoma; FISH, fluorescence in situ hybridization; GEP, gene expression profiling; MBAIT, melanocytic BAP1-mutated atypical intradermal tumor; MEKI, mitogen-activated protein kinase inhibitor; MIS LM type, melanoma in situ lentigo maligna type; MMS, Mohs micrographic surgery; NCCN, National Comprehensive Cancer Network; RT, radiation therapy; SLN, sentinel lymph node; SLNB, sentinel lymph node biopsy; WE, wide excision



Management of Primary Cutaneous Melanoma

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