Bleeding Prophylaxis in Bleeding Disorder Patients Undergoing GI Endoscopy

Publication Date: March 16, 2020
Last Updated: March 14, 2022

Recommendations

For All Bleeding Disorder Patients

Advise pre-treatment with antifibrinolytic therapy,* continue for 5 days if forceps biopsy or polypectomy for polyp <8 mm, up to 10 days if larger polyp or endoscopic mucosal resection or endoscopic variceal ligation or ERCP with sphincterotomy or hemorrhoidectomy.

* antifibrinolytic therapy-tranexamic acid 1.3 g PO tid or epsilon aminocaproic acid 50–100mg/kg PO q6h beginning 1–24 hrs pre-procedure.

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Overview

Title

Bleeding Prophylaxis in Bleeding Disorder Patients Undergoing GI Endoscopy

Authoring Organization

National Hemophilia Foundation