Use of Opioids for Cancer Pain

Publication Date: December 5, 2022

Key Points

Key Points

  • Moderate-to-severe pain can be effectively manged with opioids, though serious challenges to their use exist, including well-characterized adverse events.
  • As a result of opioid misuse, opioid-related deaths and other challenges, people with cancer report stigma and concern related to opioid use.
  • Patients express fear of “addiction” along with guilt and a sense of moral failure that they require opioids, causing some to skip a dose or take a lower dose than prescribed.

Treatment

...atment...

Recommendation 1.1Opioids should b...


...dation 1.2Prior to initiating opioid the...


...tion 2.1For patients who are candidates to begin...


...tion 2.2Clinicians with limited experience w...


...3.1Opioids should be initiated at th...


...dation 3.2Opioids should be initiate...


...tion 3.3Patients who have been taking...


...ation 3.4Evidence remains insufficient to...


...ion 3.5Evidence remains insufficient...


Recommendation 3.6For patients with a substance...


...tion 4Clinicians should proactively...


...tion 5.1For patients with renal impai...


...ndation 5.2For patients with renal or hepatic im...


...ecommendations 6.1In patients receiving op...


...mendation 6.2Evidence remains insufficient to re...


...dation 7Opioid rotation should be off...


...revention and Management of Opioid-In...