Use of Opioids for Cancer Pain

Publication Date: December 5, 2022

Key Points

Key Points

  • Moderate-to-severe pain can be effectively manged with opioids, though serious challenges to their use exist, including well-characterized adverse events.
  • As a result of opioid misuse, opioid-related deaths and other challenges, people with cancer report stigma and concern related to opioid use.
  • Patients express fear of “addiction” along with guilt and a sense of moral failure that they require opioids, causing some to skip a dose or take a lower dose than prescribed.

Treatment

...reatment...

...endation 1.1Opioids should be offered...


...ion 1.2Prior to initiating opioid therapy, clinici...


...mendation 2.1For patients who are candid...


...mendation 2.2Clinicians with limited experience...


...3.1Opioids should be initiated at the l...


...mmendation 3.2Opioids should be in...


...ion 3.3Patients who have been taking other...


...mmendation 3.4Evidence remains insuf...


...ommendation 3.5Evidence remains insuffi...


...endation 3.6For patients with a substance use diso...


...n 4Clinicians should proactively offer...


...on 5.1For patients with renal impairment c...


...tion 5.2For patients with renal or hepatic...


...mendations 6.1In patients receiving...


...ndation 6.2Evidence remains insufficient to recom...


...ation 7Opioid rotation should be of...


...tion and Management of Opioid-Induced...