Use of Opioids for Cancer Pain

Publication Date: December 5, 2022

Key Points

Key Points

  • Moderate-to-severe pain can be effectively manged with opioids, though serious challenges to their use exist, including well-characterized adverse events.
  • As a result of opioid misuse, opioid-related deaths and other challenges, people with cancer report stigma and concern related to opioid use.
  • Patients express fear of “addiction” along with guilt and a sense of moral failure that they require opioids, causing some to skip a dose or take a lower dose than prescribed.

Treatment

...atment...

...1.1Opioids should be offered to patients with mo...


...1.2Prior to initiating opioid therapy, clinicia...


....1For patients who are candidates to begin opioid...


...ecommendation 2.2Clinicians with limited experien...


...ndation 3.1Opioids should be initiated...


...dation 3.2Opioids should be initia...


...mendation 3.3Patients who have been taking other...


...3.4Evidence remains insufficient to recommend for...


...n 3.5Evidence remains insufficient to rec...


...ommendation 3.6For patients with a s...


...mendation 4Clinicians should proactively offer e...


...tion 5.1For patients with renal impairment curren...


...ndation 5.2For patients with renal or hepat...


...ions 6.1In patients receiving opioids around the...


...mendation 6.2Evidence remains insufficient...


...ion 7Opioid rotation should be offered...


...1. Prevention and Management of Opioid-In...