Use of Opioids for Cancer Pain
Key Points
Key Points
- Moderate-to-severe pain can be effectively manged with opioids, though serious challenges to their use exist, including well-characterized adverse events.
- As a result of opioid misuse, opioid-related deaths and other challenges, people with cancer report stigma and concern related to opioid use.
- Patients express fear of “addiction” along with guilt and a sense of moral failure that they require opioids, causing some to skip a dose or take a lower dose than prescribed.
Treatment
...eatment
...tion 1.1Opioids should be offered to patients...
....2Prior to initiating opioid therapy, clin...
...on 2.1For patients who are candidat...
...commendation 2.2Clinicians with limit...
...ation 3.1Opioids should be initiated at the lowes...
...3.2Opioids should be initiated as imme...
...endation 3.3Patients who have been t...
...mmendation 3.4Evidence remains insu...
...ommendation 3.5Evidence remains insufficient to...
...ommendation 3.6For patients with a sub...
...tion 4Clinicians should proactively of...
...tion 5.1For patients with renal impairment...
...ation 5.2For patients with renal or hepatic impa...
...6.1In patients receiving opioids a...
...ation 6.2Evidence remains insufficient...
...n 7Opioid rotation should be offered to patien...
...ble 1. Prevention and Management of Opioid-I...