Prevention of Central Line-Associated Bloodstream Infections in the Neonatal Intensive Care Unit

Authoring Organization

Publication Month/Year

March 4, 2022

Last Updated Month/Year

August 14, 2023

Document Type


Country of Publication


Target Patient Population

NICU patients

Target Provider Population

Neonatologists, Pediatricians, Infection Control

Inclusion Criteria

Male, Female, Infant

Health Care Settings


Intended Users

Nurse, nurse practitioner, physician, physician assistant



Diseases/Conditions (MeSH)

D001424 - Bacterial Infections


central line-associated bloodstream infection (CLABSI), Central Venous Catheter, CLABSI, NICU, neonatal intensive care unit, PICC, chlorhexidine gluconate, skin antisepsis, CVC dressing, CHG-impregnated dressings, alcohol disinfectant caps, CHG bathing, laboratory stewardship, diagnostic stewardship, prophylactic antimicrobial lock, peripherally inserted central catheter, neonatal vascular access team

Source Citation

Muller M, Bryant KA, Espinosa C, Jones JA, Quach C, Rindels JR, Stewart DL, Zangwill KM, Sánchez PJ. SHEA neonatal intensive care unit (NICU) white paper series: Practical approaches for the prevention of central line-associated bloodstream infections. Infect Control Hosp Epidemiol. 2022 Mar 4:1-46. doi: 10.1017/ice.2022.53. PMID: 35241185.