Management of Individuals with Diabetes at High Risk for Hypoglycemia

Publication Date: December 7, 2022

Key Points

Key Points

  • Hypoglycemia is associated with a number of unwanted outcomes including distress in those with diabetes and their caregivers, reductions in quality of life, and reductions in medication adherence, leading to increased risks for diabetes-related comorbidities.
  • Individuals with type 1 diabetes (T1D) may have clinically significant episodes of hypoglycemia as often as twice per week.
  • Those with type 2 diabetes (T2D) are at lower risk for hypoglycemia unless they have specific clinical characteristics that increase that risk, including the use of medications known to be associated with hypoglycemia (e.g., insulin, sulfonylureas), long duration of diabetes, and renal and/or hepatic dysfunction.

Definition of Terms

...Definition of Terms...

...Real-time continuous glucose monitoring...


Evaluation

...Evaluation...

...at High Risk for Developing Hypoglycem...


Treatment

...Treatment...

...dation 1Endocrine Society (ES) recomme...

...on 2ES suggests using real-time CGM and A...

...3ES suggests real-time CGM be used rather than no...

Recommendation 4ES suggests initiation of...


...Table 3. Recommen...


...Table 4. Elements Neede...


...mmendation 5ES suggests continuati...

...mmendation 6ES recommends that inpatient glyc...

...commendation 7ES suggests long-acting insulin a...


...ntly Available Insulin Preparations...


...mendation 8ES suggests that rapid-acti...

...mmendation 9ES recommends that a structu...


...Table...


...n 10ES recommends that glucagon prep...


...Table 7. Curren...