Management of Individuals with Diabetes at High Risk for Hypoglycemia

Publication Date: December 7, 2022

Key Points

Key Points

  • Hypoglycemia is associated with a number of unwanted outcomes including distress in those with diabetes and their caregivers, reductions in quality of life, and reductions in medication adherence, leading to increased risks for diabetes-related comorbidities.
  • Individuals with type 1 diabetes (T1D) may have clinically significant episodes of hypoglycemia as often as twice per week.
  • Those with type 2 diabetes (T2D) are at lower risk for hypoglycemia unless they have specific clinical characteristics that increase that risk, including the use of medications known to be associated with hypoglycemia (e.g., insulin, sulfonylureas), long duration of diabetes, and renal and/or hepatic dysfunction.

Definition of Terms

...inition of Terms

...l-time continuous glucose monitoring (CGM) inv...


Evaluation

Evaluat...

...ons at High Risk for Developing Hypog...


Treatment

...eatment...

...ecommendation 1Endocrine Society (ES) r...

...mmendation 2ES suggests using real-time CGM and AD...

...commendation 3ES suggests real-time CGM be used ra...

...on 4ES suggests initiation of CGM in the...


Table 3. Recommended Candidates for the Initi...


...ements Needed for Initiation of Continu...


...ecommendation 5ES suggests continuation of person...

...ation 6ES recommends that inpatien...

...tion 7ES suggests long-acting insulin analog...


...rently Available Insulin PreparationsHavi...


...commendation 8ES suggests that rapid-acti...

...mendation 9ES recommends that a struct...


...le 6. Elements of a Structured Diabetes Education...


...n 10ES recommends that glucagon preparations that...


...urrently Available Glucagon Preparations...