Management of Individuals with Diabetes at High Risk for Hypoglycemia

Publication Date: December 7, 2022

Key Points

Key Points

  • Hypoglycemia is associated with a number of unwanted outcomes including distress in those with diabetes and their caregivers, reductions in quality of life, and reductions in medication adherence, leading to increased risks for diabetes-related comorbidities.
  • Individuals with type 1 diabetes (T1D) may have clinically significant episodes of hypoglycemia as often as twice per week.
  • Those with type 2 diabetes (T2D) are at lower risk for hypoglycemia unless they have specific clinical characteristics that increase that risk, including the use of medications known to be associated with hypoglycemia (e.g., insulin, sulfonylureas), long duration of diabetes, and renal and/or hepatic dysfunction.

Definition of Terms

Definition of Ter...

...time continuous glucose monitoring (CGM) inv...


Evaluation

...aluation...

Table 1. Persons at High Risk for D...


Treatment

Treatme...

...on 1Endocrine Society (ES) recommends CG...

...ommendation 2ES suggests using real-ti...

...tion 3ES suggests real-time CGM be used rather tha...

...mmendation 4ES suggests initiation of CGM in th...


...commended Candidates for the Initiation of Inpatie...


...lements Needed for Initiation of Continuous...


...n 5ES suggests continuation of perso...

...ation 6ES recommends that inpatient glycemic sur...

...mmendation 7ES suggests long-acting insulin...


...rrently Available Insulin PreparationsHaving t...


Recommendation 8ES suggests that rapid-ac...

...ndation 9ES recommends that a structured progra...


...lements of a Structured Diabetes Education Pro...


...mmendation 10ES recommends that glucagon...


...ble 7. Currently Available Glucagon Pre...