Management of Individuals with Diabetes at High Risk for Hypoglycemia

Publication Date: December 6, 2022

Key Points

Key Points

  • Hypoglycemia is associated with a number of unwanted outcomes including distress in those with diabetes and their caregivers, reductions in quality of life, and reductions in medication adherence, leading to increased risks for diabetes-related comorbidities.
  • Individuals with type 1 diabetes (T1D) may have clinically significant episodes of hypoglycemia as often as twice per week.
  • Those with type 2 diabetes (T2D) are at lower risk for hypoglycemia unless they have specific clinical characteristics that increase that risk, including the use of medications known to be associated with hypoglycemia (e.g., insulin, sulfonylureas), long duration of diabetes, and renal and/or hepatic dysfunction.

Definition of Terms

...nition of Terms...

...-time continuous glucose monitoring (CG...


Evaluation

...valuatio...

...s at High Risk for Developing Hypoglycemia I...


Treatment

...eatment...

...dation 1Endocrine Society (ES) recommends CGM ra...

...n 2ES suggests using real-time CGM...

...n 3ES suggests real-time CGM be used rather tha...

...ecommendation 4ES suggests initiatio...


.... Recommended Candidates for the Initiation o...


...ble 4. Elements Needed for Initiation of Cont...


...ommendation 5ES suggests continuation o...

...ommendation 6ES recommends that in...

...ecommendation 7ES suggests long-acting insulin an...


...ly Available Insulin PreparationsHaving tro...


...tion 8ES suggests that rapid-actin...

...ES recommends that a structured program of p...


...6. Elements of a Structured Diabetes...


...dation 10ES recommends that glucagon preparatio...


...tly Available Glucagon Preparations...