Hypercalcemia of Malignancy in Adults
Key Points
Key Points
- Hypercalcemia of malignancy (HCM), a condition associated with high morbidity and mortality, is the most common metabolic complication of malignancies.
- All adults with HCM should receive treatment with denosumab (Dmab) or an intravenous (IV) bisphosphonate (BP).
- Adults with calcitriol-mediated HCM should first be treated with glucocorticoids, with the addition of Dmab or an IV BP if glucocorticoid therapy is insufficient.
Treatment
...Treatment
...endation 1In adults with HCM, Endocrine...
...ion 2In adults with HCM, ES suggests treatment...
...commendation 3In adults with severe...
...tion 4In adults with refractory/recurrent HCM on...
...ndation 5In adults with HCM from tumors associ...
...6In adult patients with hypercalcemia...
...n 7In adult patients with hypercalcemia due t...
...on 8In adult patients with hypercalcemia...
...Good...
...ults with HCM, adequate hydration with IV...
UGPS 2In adults with HCM, dental hygiene an...
...with HCM who receive antiresorptive therapy, v...
...PS 4In adults with HCM, renal function (creati...
UGPS 5In adults with HCM and renal...
UGPS 6In adults with HCM, serum magnesiu...
...In adults with HCM, clinical oncology...
...dults with hypercalcemia due to parathyroid c...
...1. Treatment Regimens for Hypercalcemia of...
...ggested Workflow for the Management of Hyperca...
...x A: Common Terminology Criteria for Adverse...