Hypercalcemia of Malignancy in Adults
Key Points
Key Points
- Hypercalcemia of malignancy (HCM), a condition associated with high morbidity and mortality, is the most common metabolic complication of malignancies.
- All adults with HCM should receive treatment with denosumab (Dmab) or an intravenous (IV) bisphosphonate (BP).
- Adults with calcitriol-mediated HCM should first be treated with glucocorticoids, with the addition of Dmab or an IV BP if glucocorticoid therapy is insufficient.
Treatment
...Treatment...
...1In adults with HCM, Endocrine Society (...
...ndation 2In adults with HCM, ES suggests treatme...
...mendation 3In adults with severe HCM (serum calci...
...tion 4In adults with refractory/re...
...In adults with HCM from tumors associat...
...ecommendation 6In adult patients with hyper...
...ndation 7In adult patients with hypercalcemi...
...mmendation 8In adult patients with hy...
...Good Pr...
...with HCM, adequate hydration with IV fluids is fi...
...S 2In adults with HCM, dental hygiene...
...3In adults with HCM who receive antireso...
...In adults with HCM, renal function (creatin...
...s with HCM and renal insufficiency (de...
...In adults with HCM, serum magnesium and...
UGPS 7In adults with HCM, clinical oncology consu...
...s with hypercalcemia due to parathyro...
...1. Treatment Regimens for Hypercal...
...e 1. Suggested Workflow for the Managemen...
...x A: Common Terminology Criteria for Adverse Event...