Hypercalcemia of Malignancy in Adults
Key Points
Key Points
- Hypercalcemia of malignancy (HCM), a condition associated with high morbidity and mortality, is the most common metabolic complication of malignancies.
- All adults with HCM should receive treatment with denosumab (Dmab) or an intravenous (IV) bisphosphonate (BP).
- Adults with calcitriol-mediated HCM should first be treated with glucocorticoids, with the addition of Dmab or an IV BP if glucocorticoid therapy is insufficient.
Treatment
...eatment...
...n 1In adults with HCM, Endocrine Society (ES) reco...
Recommendation 2In adults with HCM, ES...
...dation 3In adults with severe HCM (s...
...commendation 4In adults with refractory/recurrent...
...dation 5In adults with HCM from tumors assoc...
...In adult patients with hypercalcemia...
...In adult patients with hypercalcemia...
...ndation 8In adult patients with hypercalcemia...
Good Practice Statements
...1In adults with HCM, adequate hydration with...
...2In adults with HCM, dental hygiene and oral...
...ts with HCM who receive antiresorptiv...
...adults with HCM, renal function (creatinine clear...
...ts with HCM and renal insufficiency (...
...ts with HCM, serum magnesium and phosph...
...lts with HCM, clinical oncology con...
...GPS 8In adults with hypercalcemia due to...
...ent Regimens for Hypercalcemia of MalignancyHa...
...ested Workflow for the Management...
...ommon Terminology Criteria for Adverse Events...