Diagnosis and Management of Gastrointestinal Subepithelial Lesions

We suggest EUS be performed preferentially compared with endoscopy or contrast-enhanced cross-sectional imaging for the diagnosis of nonlipomatous SEL. (C, VL)

We suggest either submucosal tunneling endoscopic resection (STER) or surgical resection for the management of SEL originating from the muscularis propria layer of the esophagus and gastroesophageal junction when resection is necessary. (C, VL)