Nonpharmacologic and Pharmacologic Treatments of Adults in the Acute Phase of Major Depressive Disorder
Publication Date: January 24, 2023
Last Updated: January 31, 2023
Summary of Recommendations
Recommendation 1a
ACP recommends monotherapy with either cognitive behavioral therapy or a second-generation antidepressant as initial treatment in patients in the acute phase of moderate to severe major depressive disorder. (S, M)
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Title
Nonpharmacologic and Pharmacologic Treatments of Adults in the Acute Phase of Major Depressive Disorder
Authoring Organization
American College of Physicians