Management of Severe Traumatic Brain Injury

Bifrontal DC is not recommended to improve outcomes as measured by the GOS-E score (Glasgow Outcome Scale—Extended) at 6 mo post-injury in severe traumatic brain injury (TBI) patients with diffuse injury (without mass lesions), and with , intracranial pressure (ICP) elevation to values >20 mm Hg for more than 15 min within a 1-h period that are refractory to first-tier therapies. However, this procedure has been demonstrated to reduce ICP and to minimize days in the intensive care unit (ICU). (Level IIA)