Quantitative Image Analysis of Human Epidermal Growth Factor Receptor 2 Immunohistochemistry for Breast Cancer

1. Laboratories that choose to implement quantitative image analysis (QIA) for human epidermal growth factor receptor 2 (HER2) immunohistochemistry interpretation for clinical testing should select a QIA system that is validated for diagnostic interpretation. The final reporting schema should be consistent with the American Society of Clinical Oncology and the College of American Pathologists guideline ‘‘Recommendations for Human Epidermal Growth Factor 2 Testing in Breast Cancer.’’ (Expert Consensus Opinion)