Biomarkers in Ulcerative Colitis

Publication Date: February 21, 2023

Key Points

Key Points

  • There is an important need for understanding how noninvasive biomarkers may serve as accurate and reliable surrogates for endoscopic assessment of inflammation.
  • Commonly available biomarkers are well-established as surrogate tests for endoscopic assessment of disease and in longitudinal monitoring of patients with an established diagnosis of ulcerative colitis (UC).
  • This guideline focuses on the following biomarkers: serum C-reactive protein (CRP), fecal calprotectin, and fecal lactoferrin.

Diagnosis

...gnosis...

...ummary of Recommendations

...lcerative Colitis in Symptomatic Rem...

...patients with UC in symptomatic remissio...

...calprotectin...

...mal fecal lactoferrin (C, L)620

...L)Implementation consideration:...

...n patients with UC in symptomatic remi...

Patients With Symptomatically Active...

...ts with symptomatically active UC, the...

...protectin >150 μg/g (C, L)620...

elevated fecal lactoferrin (C, VL...

...d CRP (C, M)620...

...n patients with UC with mild symptoms, with...

...tients with UC with mild symptoms, with normal sto...

...eat-to-target Strategies for Ulcerative Co...

...with UC, the AGA makes no recommendation in fa...


...mmary of Key Considerations When Using B...


Treatment

...atment...

...ences of Diagnostic Test Results on...