Biomarkers in Ulcerative Colitis

Publication Date: February 21, 2023

Key Points

Key Points

  • There is an important need for understanding how noninvasive biomarkers may serve as accurate and reliable surrogates for endoscopic assessment of inflammation.
  • Commonly available biomarkers are well-established as surrogate tests for endoscopic assessment of disease and in longitudinal monitoring of patients with an established diagnosis of ulcerative colitis (UC).
  • This guideline focuses on the following biomarkers: serum C-reactive protein (CRP), fecal calprotectin, and fecal lactoferrin.

Diagnosis

...agnosi...

Summary of Recommendatio...

...tients With Ulcerative Colitis in Symptomatic Rem...

...th UC in symptomatic remission, the A...

...ecal calprotec...

...rmal fecal lactoferrin (C, L)6...

...VL)Implementation consideration:...

...tients with UC in symptomatic remission but elev...

...ents With Symptomatically Active Ulcer...

...symptomatically active UC, the AGA suggests...

...calprotectin >150 μg/g (C, L)6...

...al lactoferrin (C, VL)620

elevated CRP (C,...

...h UC with mild symptoms, with elevate...

...with UC with mild symptoms, with nor...

...rget Strategies for Ulcerative Colitis...

...ith UC, the AGA makes no recommendation in...


...ary of Key Considerations When Using...


Treatment

...atment...

...of Diagnostic Test Results on Patie...