Cannabis for Psychological Symptoms Including Insomnia, Anxiety, and Depression

Authoring Organization

Publication Month/Year

February 21, 2023

Document Type


Country of Publication


Document Objectives

During the treatment of cancer, 18% of patients use cannabis for symptom management. Anxiety, depression, and sleep disturbances are common symptoms in cancer. A systematic review of the evidence for cannabis use for psychological symptoms in cancer patients was undertaken to develop a guideline. Conclusion: There is no high-quality evidence to recommend the use of cannabis as an intervention for psychological symptoms in patients with cancer until more high-quality research demonstrates benefit.

Inclusion Criteria

Male, Female, Adult, Older adult

Health Care Settings


Intended Users

Nurse, nurse practitioner, physician, physician assistant


Counseling, Management

Diseases/Conditions (MeSH)

D003863 - Depression, D001007 - Anxiety, D002188 - Cannabis


cancer, depression, anxiety, Insomnia, cannabis

Source Citation

De Feo G, Case AA, Crawford GB, Hui D, To J, Sbrana A, Alderman B, Mukhopadhyay S, Bouleuc C, Amano K, Tanco K, Garsed J, Davis M. Multinational Association of Supportive Care in Cancer (MASCC) guidelines: cannabis for psychological symptoms including insomnia, anxiety, and depression. Support Care Cancer. 2023 Feb 21;31(3):176. doi: 10.1007/s00520-023-07628-3. PMID: 36809575.