AUA/SUO Early Detection of Prostate Cancer Guideline Summary - Guideline Central

Document Overview

Design and created by Guideline Central in participation with the American Urological Association and Society of Urologic Oncology.

Document Overview

Document Title: Early Detection of Prostate Cancer

Authoring Societies

American Urological Association

Society of Urologic Oncology

Document Publication Date: Feb 25, 2026

Page Last Reviewed/Updated: Jun 24, 2026

Document Type: Guideline

Country of Publication: United States

Full Text Freely Available: Yes

Full Text Guideline: www.auanet.org/guidelines-and-quality/guidelines/early-detection-of-prostate-cancer-guideline

Source Citation: Lin DW, Carlsson S, Filson CP, et al. Updates to Early Detection of Prostate Cancer: AUA/SUO Guideline (2026).J Urol. 0(0).10.1097/JU.0000000000004995. https://www.auajournals.org/doi/10.1097/JU.0000000000004995

Supplemental Implementation Resources

Algorithm

Document Scope, Criteria, and Use Cases

Document Objectives: The recommendations discussed on the early detection of prostate cancer provide a framework to facilitate clinical decision-making in the implementation of prostate cancer screening and follow-up. This update provides several new insights, including revised strength of evidence based on recently published literature on the use of MRI in biopsy-naïve patients and biopsy techniques, updates on available biomarkers, and revised recommendations for atypical small acinar proliferation. This Guideline will require future review and updates, as early detection and diagnostic strategies in this space continue to evolve.

Scope: Assessment and Screening, Diagnosis

Diseases/Conditions (MeSH)

D011467 - Prostate

D017430 - Prostate-Specific Antigen

D055088 - Early Detection of Cancer

Keywords: Early Detection, PsA, cancer screening, early detection of cancer, prostate cancer, prostate imaging

Inclusion Criteria: Male, Adult, Older Adult

Health Care Settings: Ambulatory, Outpatient, Radiology Services

Intended Users: Nurse, Nurse Practitioner, Physician, Physician Assistant

Recommendation Development Processes & Methodology

Number of Source Documents: 330

Literature Search Start Date: Saturday, January 1, 2000

Literature Search End Date: Tuesday, November 1, 2022

Includes peer/external review process?: Yes

Includes public comment process?: Yes

Methodologist involvement?: Yes

Patient involvement?: Yes

Includes multi-disciplinary group?: Yes

Includes systematic review?: Yes

Grades quality of strength of evidence?: Yes

Grades quality of strength of recommendation?: Yes

Discloses funding source?: Yes

Discloses conflicts of interest?: Yes

Includes benefits/harms analysis with recommendations?: Yes

Identifies study selection process?: Yes

Identifies study selection criteria?: Yes

Identifies methods used to evaluate and analyze the evidence?: Yes

Identifies key questions addressed by the systematic review?: Yes

Identifies search strategy?: Yes