Chronic Idiopathic Constipation

Publication Date: May 18, 2023

Key Points

Key Points

  • Chronic idiopathic constipation (CIC) is a common clinical diagnosis that affects approximately 8%–12% of the US population.
  • Nonpharmacological therapies often represent the initial steps in management and may include dietary recommendations (such as increased fluid intake and increased dietary fiber) and behavioral changes (such as exercise). Pharmacological treatment may include the use of over-the-counter (OTC) or prescription medications, such as polyethylene glycol (PEG), secretagogues, or prokinetic agents.
  • A significant proportion of patients with CIC are not satisfied with their treatment and may use multiple OTC medications, followed by prescription medications before they have improvement in their symptoms.

Treatment

Treatment

Fibe...

...endation 1In adults with CIC, the panel sugges...


...otic laxatives

...ion 2In adults with CIC, the panel recommen...

...In adults with CIC, the panel suggests the use of...

...In adults with CIC who fail or are intoleran...


...mulant laxati...

Recommendation 5In adults with CIC, the panel reco...

...ndation 6In adults with CIC, the panel suggests t...


...ecretagog...

...In adults with CIC who do not respond to OTC...

Recommendation 8In adults with CIC...

...n 9In adults with CIC who do not respond to...


...otonin type 4 (5-HT4) Agonist

...commendation 10In adults with CIC...


...implementation considerations are based on...


...1. Overview of Interventions for the Pharmacologi...