Chronic Idiopathic Constipation

Publication Date: May 19, 2023

Key Points

Key Points

  • Chronic idiopathic constipation (CIC) is a common clinical diagnosis that affects approximately 8%–12% of the US population.
  • Nonpharmacological therapies often represent the initial steps in management and may include dietary recommendations (such as increased fluid intake and increased dietary fiber) and behavioral changes (such as exercise). Pharmacological treatment may include the use of over-the-counter (OTC) or prescription medications, such as polyethylene glycol (PEG), secretagogues, or prokinetic agents.
  • A significant proportion of patients with CIC are not satisfied with their treatment and may use multiple OTC medications, followed by prescription medications before they have improvement in their symptoms.

Treatment

Treatment

...iber...

...1In adults with CIC, the panel suggests the use...


...tic laxatives...

...ommendation 2In adults with CIC, the panel rec...

...n 3In adults with CIC, the panel suggests the use...

...tion 4In adults with CIC who fail or are intolera...


...ulant laxative...

...dation 5In adults with CIC, the panel re...

...ndation 6In adults with CIC, the pan...


...cretagogu...

...endation 7In adults with CIC who do not re...

Recommendation 8In adults with CIC who do n...

...ion 9In adults with CIC who do not respond to...


...in type 4 (5-HT4) Agonist...

...10In adults with CIC who do not respond to OTC...


...ntation considerations are based on...


...iew of Interventions for the Pharma...