Chronic Idiopathic Constipation

Publication Date: May 18, 2023

Key Points

Key Points

  • Chronic idiopathic constipation (CIC) is a common clinical diagnosis that affects approximately 8%–12% of the US population.
  • Nonpharmacological therapies often represent the initial steps in management and may include dietary recommendations (such as increased fluid intake and increased dietary fiber) and behavioral changes (such as exercise). Pharmacological treatment may include the use of over-the-counter (OTC) or prescription medications, such as polyethylene glycol (PEG), secretagogues, or prokinetic agents.
  • A significant proportion of patients with CIC are not satisfied with their treatment and may use multiple OTC medications, followed by prescription medications before they have improvement in their symptoms.

Treatment

Treatme...

Fiber

Recommendation 1In adults with CIC, the pan...


...ic laxatives...

...ndation 2In adults with CIC, the pan...

...on 3In adults with CIC, the panel suggests the us...

...commendation 4In adults with CIC who fail or are i...


...imulant laxativ...

Recommendation 5In adults with CIC, the pan...

...commendation 6In adults with CIC, the...


Secretagogu...

...mmendation 7In adults with CIC who do not...

...mmendation 8In adults with CIC who do not res...

...In adults with CIC who do not respond to OTC...


...in type 4 (5-HT4) Agonist...

...0In adults with CIC who do not respond to OTC...


...tion considerations are based on t...


...verview of Interventions for the Pharmacological...