Chronic Idiopathic Constipation

Publication Date: May 19, 2023

Key Points

Key Points

  • Chronic idiopathic constipation (CIC) is a common clinical diagnosis that affects approximately 8%–12% of the US population.
  • Nonpharmacological therapies often represent the initial steps in management and may include dietary recommendations (such as increased fluid intake and increased dietary fiber) and behavioral changes (such as exercise). Pharmacological treatment may include the use of over-the-counter (OTC) or prescription medications, such as polyethylene glycol (PEG), secretagogues, or prokinetic agents.
  • A significant proportion of patients with CIC are not satisfied with their treatment and may use multiple OTC medications, followed by prescription medications before they have improvement in their symptoms.

Treatment

...eatment...

...iber

...tion 1In adults with CIC, the panel suggests the...


...tic laxatives...

...ommendation 2In adults with CIC, the p...

...3In adults with CIC, the panel suggests the use...

...endation 4In adults with CIC who fail or are i...


...mulant laxative...

...endation 5In adults with CIC, the panel recommend...

...mendation 6In adults with CIC, the...


Secretagogue...

...ecommendation 7In adults with CIC who do not respo...

...on 8In adults with CIC who do not respond to OTC...

...In adults with CIC who do not respond to...


...type 4 (5-HT4) Agonist...

...commendation 10In adults with CIC who do no...


...implementation considerations are based on the...


...verview of Interventions for the Pharmacolog...