Chronic Idiopathic Constipation

Publication Date: May 18, 2023

Key Points

Key Points

  • Chronic idiopathic constipation (CIC) is a common clinical diagnosis that affects approximately 8%–12% of the US population.
  • Nonpharmacological therapies often represent the initial steps in management and may include dietary recommendations (such as increased fluid intake and increased dietary fiber) and behavioral changes (such as exercise). Pharmacological treatment may include the use of over-the-counter (OTC) or prescription medications, such as polyethylene glycol (PEG), secretagogues, or prokinetic agents.
  • A significant proportion of patients with CIC are not satisfied with their treatment and may use multiple OTC medications, followed by prescription medications before they have improvement in their symptoms.

Treatment

...atment...

...iber...

Recommendation 1In adults with CIC, the panel...


...ic laxatives...

...dation 2In adults with CIC, the pa...

...commendation 3In adults with CIC, the panel su...

...commendation 4In adults with CIC who fail or a...


...lant laxatives...

...dation 5In adults with CIC, the panel reco...

...on 6In adults with CIC, the panel suggest...


...ecretagogues...

Recommendation 7In adults with CIC who do not res...

...endation 8In adults with CIC who do not respon...

...ation 9In adults with CIC who do not res...


Serotonin type 4 (5-HT4) Agon...

...ecommendation 10In adults with CIC who do not resp...


...tation considerations are based on...


...Overview of Interventions for the Pha...