Neuroprognostication in Adults with Guillain-Barré Syndrome

Authoring Organization

Publication Month/Year

March 25, 2023

Last Updated Month/Year

September 11, 2023

Document Type


Country of Publication


Document Objectives

Guillain-Barré syndrome (GBS) often carries a favorable prognosis. Of adult patients with GBS, 10-30% require mechanical ventilation during the acute phase of the disease. After the acute phase, the focus shifts to restoration of motor strength, ambulation, and neurological function, with variable speed and degree of recovery. The objective of these guidelines is to provide recommendations on the reliability of select clinical predictors that serve as the basis of neuroprognostication and provide guidance to clinicians counseling adult patients with GBS and/or their surrogates.

Inclusion Criteria

Male, Female, Adult, Older adult

Health Care Settings

Hospital, Outpatient

Intended Users

Nurse, nurse practitioner, physician, physician assistant


Management, Rehabilitation

Diseases/Conditions (MeSH)

D020275 - Guillain-Barre Syndrome


Guillain-Barre syndrome, neuroprognostication, Guillain-Barré Syndrome, GBS

Source Citation

Busl KM, Fried H, Muehlschlegel S, Wartenberg KE, Rajajee V, Alexander SA, Creutzfeldt CJ, Fontaine GV, Hocker SE, Hwang DY, Kim KS, Madzar D, Mahanes D, Mainali S, Meixensberger J, Sakowitz OW, Varelas PN, Westermaier T, Weimar C. Guidelines for Neuroprognostication in Adults with Guillain-Barré Syndrome. Neurocrit Care. 2023 Jun;38(3):564-583. doi: 10.1007/s12028-023-01707-3. Epub 2023 Mar 25. Erratum in: Neurocrit Care. 2023 Apr 26;: PMID: 36964442; PMCID: PMC10241707.

Supplemental Methodology Resources

Data Supplement, Data Supplement, Data Supplement