Patent Foramen Ovale
Key Points
Key Points
- For patients with cryptogenic stroke and PFO, percutaneous PFO closure probably reduces the risk of stroke recurrence (HR-0.41, summary rate difference -0.67% per year), probably is associated with a periprocedural complication rate of 3.9%, and probably is associated with the development of serious non-periprocedural atrial fibrillation (RR-2.72, summary rate difference 0.33% per year).
- For patients with cryptogenic stroke and PFO, anticoagulation medication and antiplatelet medication are possibly equally effective at reducing recurrent stroke.
Management
...nagement...
...ndations Regarding Percutaneous PFO Closur...
...being considered for PFO closure, clinicians sh...
...ts being considered for PFO closure, clinicians sh...
...atients being considered for PFO closure,...
...s being considered for PFO closure,...
...nts being considered for PFO closure thought to...
...g considered for PFO closure, clinicia...
...n patients being considered for PFO closure, clin...
...nts being considered for PFO closure,...
...rgoing PFO closure, patients should b...
...alternative mechanism of stroke is identified, cl...
...undergoing PFO closure, patients should...
...n patients with a PFO detected after stroke and n...
...patients younger than 60 years with a PFO...
...inform patients that presence of a large shunt p...
...may be offered in other populations, such as...
...losure may be offered to younger patients (e.g.,...
...ent for whom PFO closure is being consi...
...ns Regarding Medical Therapy...
...n patients who opt to receive medical therapy...
...ients who would otherwise be considered...
...ure 1. Management Algori...