Estrogen and Progesterone Receptor Testing in Breast Cancer

Authoring Organizations

Publication Month/Year

January 13, 2020

Last Updated Month/Year

February 20, 2024

Document Type


External Publication Status


Country of Publication


Document Objectives

To update key recommendations of the American Society of Clinical Oncology/College of American Pathologists estrogen (ER) and progesterone receptor (PgR) testing in breast cancer guideline

Inclusion Criteria

Female, Adult, Older adult

Health Care Settings

Ambulatory, Hospital, Laboratory services, Outpatient

Intended Users

Nurse, nurse practitioner, physician, physician assistant


Diagnosis, Assessment and screening

Diseases/Conditions (MeSH)

D011960 - Receptors, Estrogen, D011374 - Progesterone, D011980 - Receptors, Progesterone


breast cancer, estrogen, progesterone, cancer, estrogen receptor, progesterone receptors, testing, Breast Cancer

Source Citation

Allison KH, Hammond MEH, Dowsett M, McKernin SE, Carey LA, Fitzgibbons PL, Hayes DF, Lakhani SR, Chavez-MacGregor M, Perlmutter J, Perou CM, Regan MM, Rimm DL, Symmans WF, Torlakovic EE, Varella L, Viale G, Weisberg TF, McShane LM, Wolff AC. Estrogen and Progesterone Receptor Testing in Breast Cancer: ASCO/CAP Guideline Update. J Clin Oncol. 2020 Apr 20;38(12):1346-1366. doi: 10.1200/JCO.19.02309. Epub 2020 Jan 13. PMID: 31928404.

Supplemental Methodology Resources

Data Supplement,